Influence of repeated isometric contractions on muscle deoxygenation and pulmonary oxygen uptake kinetics in humans

Clinical Physiology and Functional Imaging
Aurélien Bringard, Stéphane Perrey

Abstract

The purpose of the present study was to compare simultaneously vastus lateralis (VL) deoxygenation and pulmonary O(2) uptake (O(2)) kinetics during fatiguing knee extension exercise with minimal cardiac load. Eight healthy subjects realized an intermittent bilateral knee-extension exercise (3-s contraction/3-s relaxation) at 40% of maximum voluntary contraction for 10 min. VL deoxygenation was recorded by near infrared spectroscopy at 2 Hz (NIRO-300, Hamamatsu Photonics, Japan) and O(2) was determined breath-by-breath (K4b(2), Cosmed, Italy). After a time delay of 16 +/- 5 s, deoxygenation kinetics at the onset of exercise followed an exponential time course at a significant faster rate than O(2) (time constant of 5.4 +/- 4.0 s vs. 31.6 +/- 10.4 s, P<0.01) reflecting a mismatch between local O(2) consumption and perfusion. Thereafter, a rise in O(2) of 223 +/- 123 ml min(-1) (consistent with the mathematical model, 259 +/- 126 ml min(-1)) was observed between minutes 2 and 10. During the same exercise time, changes in tissue oxygenation index decreased significantly and were individually correlated with the corresponding increased O(2) (P<0.05), suggesting that the majority of the slow rise of O(2) arose from the exercising lim...Continue Reading

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Citations

Nov 18, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Lixin WangShigeo Fujimoto
Feb 26, 2008·Journal of Strength and Conditioning Research·Shigeo KawadaChiho Fukusaki
Sep 3, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gwenael LayecDavid Bendahan
Dec 19, 2009·Medicine and Science in Sports and Exercise·Keisho KatayamaKoji Ishida

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