PMID: 9186279Jan 1, 1997Paper

Influence of residual antegrade coronary blood flow on the long-term prognosis of medically treated patients with myocardial infarction and single-vessel disease

Japanese Heart Journal
H ImamuraA Seki

Abstract

We assessed the influence of residual antegrade coronary perfusion on long-term mortality and morbidity in 262 patients (256 men and 6 women, aged 52.3 +/- 9.8 years) with medically treated old myocardial infarction and single-vessel disease who were followed for 117.0 +/- 39.8 months. Partial or complete antegrade coronary perfusion of the infarct artery was present in 165 patients (group I); no or minimal antegrade perfusion of the infarct artery was present in 97 patients (group II). There was no significant difference in survival between group I (5-year survival rate, 96.9% and 10-year survival rate, 90.7%) and group II (93.8% and 92.7%, respectively). There was also no significant difference in the event free survival rate between group I (5-year, 92.6% and 10-year, 79.7%) and group II (89.5% and 74.8%, respectively). The extent of left ventricular dysfunction was an important determinant of prognosis: 10-year survival rates in patients with ejection fractions of > 60%, 40-60% and < 40% were 94.8%, 90.6% and 74.8%, respectively. In the majority of patients the subsequent cardiac events were related to the progression of atherosclerosis in previously nonstenotic coronary arteries. Thus the presence or absence of residual an...Continue Reading

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