Influence of sagittal and axial types of ossification of posterior longitudinal ligament on mechanical stress in cervical spinal cord: A finite element analysis

Clinical Biomechanics
Batbayar KhuyagbaatarYoon Hyuk Kim

Abstract

There are few studies focusing on the prediction of stress distribution according to the types of ossification of the posterior longitudinal ligament, which can be fundamental information associated with clinical aspects such as the relationship between stress level and neurological symptom severity. In this study, the influence of sagittal and axial types of ossification of the posterior longitudinal ligament on mechanical stress in the cervical spinal cord was investigated. A three-dimensional finite element model of the cervical spine with spinal cord was developed and validated. The von Mises stresses in the cord and the reduction in cross-sectional areas and volume of the cord were investigated for various axial and sagittal types according to the occupying ratio of ossification of the posterior longitudinal ligament in the spinal canal. The influence of axial type was less than that of the sagittal type, even though the central type showed higher maximum stresses in the cord, especially for the continuous type. With a 60% occupying ratio of ossification of the posterior longitudinal ligament, the maximum stress was significantly high and the cross-sectional area of the spinal cord was reduced by more than 30% of the intac...Continue Reading

References

Sep 10, 1998·Pediatric Neurosurgery·I G BloomfieldL E Bilston
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Nancy Epstein
Jul 17, 2008·Journal of Neurotrauma·Jason T MaikosDavid I Shreiber
Jan 21, 2010·Annals of Biomedical Engineering·Cecilia PerssonRichard M Hall
Nov 5, 2010·Journal of Neurotrauma·Cecilia PerssonRichard M Hall
Nov 29, 2011·The Journal of Spinal Cord Medicine·Norihiro NishidaToshihiko Taguchi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.