Feb 20, 2016

Influence of Sexuality in Functional Recovery after Spinal Cord Injury in Rats

Archives of Bone and Joint Surgery
Mohammadreza EmamhadiShervin Ghadarjani

Abstract

Spinal cord injury (SCI) is a major clinical condition and research is commonly done to find suitable treatment options. However, there are some degrees of spontaneous recovery after SCI and gender is said to be a contributing factor in recovery, but this is controversial. This study was done to compare the effects of sexual dimorphism on spontaneous recovery after spinal cord injury in Wistar Rats. Spinal cord lesions were made by compressing the cord at T9 level and making a spinal cord contusion. Routine care of each rat was done daily. The LSS scoring system was used to measure the locomotion of these rats and to compare the recovery rate between male and female rats. The results suggested that there was no significant difference between the two sex in recovery. To be female does not seem to be a prognostic factor for recovery after SCI. However, this preliminary study should be repeated in other animals and in larger cohorts.

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Mentioned in this Paper

Study
Research
Malignant Neoplasm of Spinal Cord
Neoplasm of Uncertain or Unknown Behavior of Spinal Cord
Sexual Dimorphism
Level of the Ninth Thoracic Vertebra
Locomotion
Spinal Cord Diseases
Benign Neoplasm of Spinal Cord
Spinal Cord Injuries

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