Influence of slice overlap on positron emission tomography image quality

Physics in Medicine and Biology
Clare McKeownCaroline Findlay

Abstract

PET scans use overlapping acquisition beds to correct for reduced sensitivity at bed edges. The optimum overlap size for the General Electric (GE) Discovery 690 has not been established. This study assesses how image quality is affected by slice overlap. Efficacy of 23% overlaps (recommended by GE) and 49% overlaps (maximum possible overlap) were specifically assessed. European Association of Nuclear Medicine (EANM) guidelines for calculating minimum injected activities based on overlap size were also reviewed. A uniform flood phantom was used to assess noise (coefficient of variation, (COV)) and voxel accuracy (activity concentrations, Bq ml(-1)). A NEMA (National Electrical Manufacturers Association) body phantom with hot/cold spheres in a background activity was used to assess contrast recovery coefficients (CRCs) and signal to noise ratios (SNR). Different overlap sizes and sphere-to-background ratios were assessed. COVs for 49% and 23% overlaps were 9% and 13% respectively. This increased noise was difficult to visualise on the 23% overlap images. Mean voxel activity concentrations were not affected by overlap size. No clinically significant differences in CRCs were observed. However, visibility and SNR of small, low contr...Continue Reading

References

Oct 28, 2003·European Journal of Nuclear Medicine and Molecular Imaging·John L HummAlberto Del Guerra
Apr 23, 2005·European Journal of Nuclear Medicine and Molecular Imaging·D VisvikisP J Ell
Jul 6, 2010·Physics in Medicine and Biology·E RapisardaM C Gilardi
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Sep 17, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Dale L Bailey, Kathy P Willowson
Dec 3, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Ronald BoellaardUNKNOWN European Association of Nuclear Medicine (EANM)

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Citations

Nov 4, 2017·Australasian Physical & Engineering Sciences in Medicine·Takuro UmedaMitsuru Koizumi
Dec 16, 2021·European Journal of Nuclear Medicine and Molecular Imaging·John DicksonMichael Lassmann

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