PMID: 2508847Sep 9, 1989Paper

Influence of smoking and plasma factors on patency of femoropopliteal vein grafts

BMJ : British Medical Journal
S WisemanJ Powell

Abstract

To determine the effects of smoking, plasma lipids, lipoproteins, apolipoproteins, and fibrinogen on the patency of saphenous vein femoropopliteal bypass grafts at one year. Prospective study of patients with saphenous vein femoropopliteal bypass grafts entered into a multicentre trial. Surgical wards, outpatient clinics, and home visits coordinated by two tertiary referral centres in London and Birmingham. 157 Patients (mean age 66.6 (SD 8.2) years), 113 with patent grafts and 44 with occluded grafts one year after bypass. Cumulative percentage patency at one year. Markers for smoking (blood carboxyhaemoglobin concentration (p less than 0.05) and plasma thiocyanate concentration (p less than 0.01) and plasma concentrations of fibrinogen (p less than 0.001) and apolipoproteins AI (p less than 0.04) and (a) (p less than 0.05) were significantly higher in patients with occluded grafts. Serum cholesterol concentrations were significantly higher in patients with grafts that remained patent one year after bypass (p less than 0.005). Analysis of the smoking markers indicated that a quarter of patients (40) were untruthful in their claims to have stopped smoking. Based on smoking markers, patency of grafts in smokers was significantly...Continue Reading

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Citations

Jul 1, 1994·The British Journal of Surgery·D J HigmanJ T Powell
Aug 1, 1994·The British Journal of Surgery·J T Powell, R M Greenhalgh
Jan 1, 1994·British Heart Journal·D J HigmanJ Moss
May 1, 1996·Cardiovascular and Interventional Radiology·B M StoeckelhuberG Kueffer
Apr 1, 1996·Arteriosclerosis, Thrombosis, and Vascular Biology·D J HigmanJ T Powell
Jan 1, 1994·The British Journal of Surgery·P A StonebridgeJ A Murie
Oct 1, 1993·The British Journal of Surgery·D J HigmanJ T Powell
Mar 30, 1999·Journal of Internal Medicine·R PedrinelliM Ferrari
May 3, 2007·Expert Opinion on Pharmacotherapy·E M FatourouD P Mikhailidis
May 15, 2015·Circulation. Cardiovascular Interventions·Jae-Sik JangJohn A Spertus
Jun 1, 1994·The British Journal of Surgery·J T Powell, D J Higman
Apr 1, 1992·Stroke; a Journal of Cerebral Circulation·M Gliksman, A Wilson
Apr 1, 1996·Anaesthesia·M R Nel, M Morgan
Feb 29, 1996·Nature·R C HicksJ T Powell
Apr 22, 2005·Journal of Thrombosis and Haemostasis : JTH·T W Meade
Jan 1, 1997·Vascular Medicine·E Ernst, W Koenig
Nov 1, 1990·Trends in Pharmacological Sciences·N S Cook, D Ubben
Mar 1, 1994·Clinica Chimica Acta; International Journal of Clinical Chemistry·B RobertY Madec
Aug 1, 1997·Journal of Cardiothoracic and Vascular Anesthesia·W Akrawi, J L Benumof
Apr 1, 1993·Atherosclerosis·E Ernst
Nov 1, 1992·European Journal of Vascular Surgery·S NydahlN Egberg
May 1, 1992·Annals of Vascular Surgery·F S Ey
Feb 1, 1990·European Journal of Vascular Surgery·S WisemanP Franks
Apr 1, 1997·Journal of Vascular Surgery·C S CartyM Dryjski
Sep 1, 1994·Baillière's Clinical Haematology·T W Meade

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