Influence of somatic state on cardiovascular measurements in pregnancy

Physiological Measurement
Lindsay A D'SilvaMichael J Lewis

Abstract

Normal pregnancy causes marked changes in cardiac and haemodynamic function but there is continuing debate about the patterns of 'normal' change. We believe that this lack of consensus is in large part caused by inappropriate assessment conditions. This study aimed to assess physiological data obtained from pregnant women during multiple steady-states and during between-state changes. The study was a longitudinal characterization of apparently healthy pregnant women aged >18 years with assessments at three antenatal stages (12-16, 26-28 and 34-36 weeks) and at 12 weeks following birth. Cardiovascular and heart rate variability (HRV) measures were quantified non-invasively during a range of states including postural manoeuvre, exercise and respiratory regulation. Cardiovascular and HRV variables were influenced by pregnancy in specific ways: (1) steady-state values were influenced differently to state-change responses; (2) cardiac output (CO) increased progressively throughout pregnancy in all states except supine rest; (3) the ΔCO response to the supine-standing manoeuvre was particularly sensitive to pregnancy stage; (4) blood pressure was unaffected by pregnancy; (6) ΔCO and ΔSBP (systolic blood pressure) were enhanced from m...Continue Reading

Associated Clinical Trials

References

Feb 1, 1993·British Journal of Obstetrics and Gynaecology·E M EkholmR U Erkkola
Feb 1, 1996·Obstetrics and Gynecology·A C van OppenH W Bruinse
Jul 1, 1997·British Journal of Obstetrics and Gynaecology·E M EkholmH V Huikuri
May 20, 1998·Journal of Electrocardiology·G SperanzaA Albiero
Apr 16, 1999·American Journal of Obstetrics and Gynecology·P K SteinJ N Rottman
Mar 10, 2000·Seminars in Perinatology·K L ThornburgM J Morton
May 4, 2000·British Journal of Anaesthesia·C D KuoY S Tsai
Nov 15, 2000·American Journal of Hypertension·A VossR Faber
Feb 18, 2006·Computers in Biology and Medicine·J FortinF Skrabal
Feb 3, 2007·International Journal of Obstetric Anesthesia·D ChamchadV A Arkoosh
Mar 10, 2007·American Journal of Obstetrics and Gynecology·Saskia RangHans Wolf
Apr 19, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·M N M VolmanJ I P de Vries
Aug 12, 2008·Clinical Physiology and Functional Imaging·Nonna HeiskanenSeppo Heinonen
Mar 17, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Manfred G MoertlDietmar Schlembach
Feb 23, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Luis San-FrutosJose M Bajo-Arenas
Mar 30, 2012·Circulation. Cardiovascular Imaging·Oana SavuJens-Uwe Voigt
May 9, 2012·Physiological Measurement·Manfred G MoertlHelmut K Lackner

❮ Previous
Next ❯

Citations

Feb 18, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Stefan Sammito, Irina Böckelmann
Aug 25, 2015·BMC Pregnancy and Childbirth·Rhiannon Emma CarpenterMichael J Lewis
Apr 5, 2016·PloS One·Shaza M MusaMohamed F Lutfi
Jun 27, 2018·Journal of Holistic Nursing : Official Journal of the American Holistic Nurses' Association·Kayla Herbell, Jaclene A Zauszniewski
Feb 25, 2020·Journal of Clinical Laboratory Analysis·Ahmad I Al-ShafeiIshag Adam
Feb 19, 2015·Physiological Measurement·R E CarpenterM J Lewis
Jan 26, 2020·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Priyanka GargKishore Kumar Deepak
Mar 7, 2019·Biomechanics and Modeling in Mechanobiology·Jason CarsonRaoul Van Loon
Nov 6, 2020·Medicine and Science in Sports and Exercise·Victoria L MeahEric J Stöhr

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
E M EkholmK J Antila
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
E M EkholmE Salminen
Hypertension Research : Official Journal of the Japanese Society of Hypertension
Mika FujimeTadashi Kimura
© 2021 Meta ULC. All rights reserved