PMID: 375340Apr 23, 1979Paper

Influence of the adrenal cortex on allograft rejections in rats

Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
J Comsa, H Leonhardt

Abstract

I. The bibliography about corticosteroid influence on immune response is briefly reviewed. Generally, it is admitted that corticosteroids are immunosuppressive when administered in large amounts. Divergent opinions are recalled. II. The aims of the experiments are summarized: A) Investigate on the influence of corticoids (given in just substitutive amounts) on skin allograft rejection. B) Investigate on possible interactions between adrenal cortex and thymus with this test. III. It was observed, that A) Adrenalectomy resulted in a significant delay of allograft rejection. B) This could be suppressed partially by administering aldosterone, corticosterone, and desoxycorticosterone and completely by administering at least two of these hormones. C) Cortisol had shown a minor inhibitory influence. D) There was no obvious difference between adrenalectomized and thymectomized rats and those adrenalectomized only. IV. These observations are replaced in the context of bibliography and their significance is discussed.

References

Feb 28, 1975·Annals of the New York Academy of Sciences·J ComsaJ A Schwarz
Nov 1, 1975·Proceedings of the Society for Experimental Biology and Medicine·H BesedovskyJ Müller
Nov 19, 1971·Biochimica Et Biophysica Acta·A D Abraham, C E Sekeris
Sep 1, 1970·Proceedings of the Society for Experimental Biology and Medicine·J F WhitfieldR H Rixon
Jan 1, 1974·Psychotherapy and Psychosomatics·R H Gisler
Jan 1, 1970·Endocrinology·H Sands, R C Haynes
Jul 1, 1974·Journal of Neurosurgery·F J EpsteinJ Ransohoff
Aug 1, 1974·Experimental Cell Research·Y KinoshitaM Fukamizu
Dec 29, 1972·Biochimica Et Biophysica Acta·O Greengard, R Machovich
Jan 1, 1971·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·A BaethmannW Brendel
Jun 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·M H MakmanA White
Oct 1, 1969·Experimental Cell Research·H Blomgren, B Andersson
Jan 1, 1969·International Archives of Allergy and Applied Immunology·G F Solomon
Jan 1, 1967·International Archives of Allergy and Applied Immunology·P Dukor, F M Dietrich
Oct 1, 1952·Physiological Reviews·T F DOUGHERTY
Nov 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·E E FISCHELC PHOTOPOULOS
May 1, 1953·Postgraduate Medical Journal·E KAWERAU
Dec 1, 1955·The Journal of Experimental Medicine·E H KASSM FINLAND
Mar 1, 1959·The American Journal of Physiology·K M KNIGGEW J SCHINDLER
Jan 15, 1960·Science·R WISTAR, W H HILDEMANN
Feb 28, 1964·Annals of the New York Academy of Sciences·T F DOUGHERTYD L BERLINER
Jan 1, 1964·The Journal of Experimental Medicine·C T AMBROSE
May 1, 1955·Canadian Journal of Biochemistry and Physiology·S E NEWSOM, M DARRACH
Jan 1, 1951·The Journal of Experimental Medicine·M BJØRNEBOEH C STOERK
Jan 1, 1951·Proceedings of the Society for Experimental Biology and Medicine·F G GERMUTHJ OYAMA
May 26, 1951·British Medical Journal·R E BILLINGHAMP B MEDAWAR
Jun 1, 1951·Endocrinology·S ROBERTS, A WHITE
Sep 1, 1951·Annals of Surgery·E H ELLISONR M ZOLLINGER
Jan 1, 1951·Transactions - American Society of Ophthalmologic and Otolaryngologic Allergy·J S FRIEDENWALDE U OWENS
May 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·S MALKIEL, B J HARGIS
May 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·M AGOSINA JARPA

❮ Previous
Next ❯

Citations

Nov 1, 1987·Journal of Clinical Immunology·R GerliP Rambotti
Sep 1, 1990·Cell and Tissue Research·M D KendallA Hamblin
May 1, 1988·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·C MartinoyaS Bloch
Jan 1, 1983·Vox Sanguinis·M S Kennedy, R E Domen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.