Influence of the carbohydrate moiety on the growth inhibitory activity and adhesiveness of 3T3 cell plasma membranes

Experientia
P J Higgins, S W Peterson

Abstract

Treatment of 3T3 cell plasma membranes with glycosidase enzymes decreased their ability to inhibit cell growth and also decreased their binding to 3T3 cells. This suggests that carbohydrate is required for complete function of inhibitory activity and that inhibition is associated with membrane adhesion.

References

Jun 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·B Whittenberger, L Glaser
May 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·R Dulbecco, M G Stoker
Jan 1, 1982·Journal of Cellular Biochemistry·M A LiebermanL Glaser
Dec 1, 1982·Experimental Cell Research·S W PetersonR Vale
Jan 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·G J TODAROB D GOLDBERG

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Citations

Oct 1, 1995·Glycoconjugate Journal·R J WieserF Oesch

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