Influence of the degree of anaemia on the prognosis of older adults with heart failure (SPAN-HF study).

Medicina clínica
J Grau Amorósen representación de los investigadores del Grupo RICA

Abstract

To assess whether a sustained optimal haemoglobin value in the 3 months after admission for heart failure (HF) decompensation reduces morbidity and mortality during the 12 months after admission for acute HF. Retrospective study of the 1408 patients older than 65 years included in the RICA registry divided into 3 groups: no anaemia (group A), recovered anaemia (group B), and persistent anaemia (group C), according to haemoglobin levels on admission, and 3 months after discharge. Kaplan-Meier curves were constructed, comparing the groups using the log-rank test and a Cox regression model was performed to analyse survival. 578 (41.1%), 299 (21.2%) and 531 (37.7%) were included in groups A, B and C, respectively. We recorded a total of 768 deaths and readmissions. There were 23 (4%), 12 (4%) and 49 (9.2%), (p=.001) individuals who died due to HF and 154 (27%), 73 (24%) and 193 (36%) (P<.001) admissions for this pathology, respectively. Patients with persistent anaemia had a higher risk of death (RR 1.29, 95% CI 1.04-1.61, P=.024) or readmission (1.92, 95% CI 1.16-3, 19; P=.012) due to HF. Persistent anaemia in the months after admission for HF increases morbidity and mortality in the subsequent year.

References

Feb 15, 2003·The American Journal of Medicine·Mikhail KosiborodHarlan M Krumholz
May 3, 2005·American Heart Journal·Joann Lindenfeld
Oct 26, 2005·Archives of Internal Medicine·Mikhail KosiborodHarlan M Krumholz
Feb 2, 2008·Journal of the American College of Cardiology·W H Wilson TangJames B Young
May 7, 2008·Revista clínica española·J Grau-AmorósUNKNOWN GESAIC Study
Aug 12, 2008·The American Journal of Medicine·Shannon M DunlayVéronique L Roger
Aug 30, 2008·Journal of the American College of Cardiology·Hessel F GroenveldPeter van der Meer
Mar 24, 2009·Medicina clínica·Jorge Grau AmorósUNKNOWN Investigadores del Estudio GESAIC
Jan 28, 2010·American Heart Journal·Pamela N PetersonFrederick A Masoudi
Mar 9, 2012·Medicina clínica·Jorge Grau-AmorósAgustín Urrutia
Feb 15, 2019·Scientific Reports·Kazuya NagaoUNKNOWN CURRENT AS Registry Investigators
Mar 9, 2019·European Heart Journal. Quality of Care & Clinical Outcomes·Andrew P AmbrosyUNKNOWN RBC HEART Investigators
Mar 11, 2020·The American Journal of Cardiology·Kartik GuptaNavkaranbir S Bajaj

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.