Influence of the dissolution rate on the collapse and shedding behavior of monostearin/monopalmitin-rich coated microbubbles

Langmuir : the ACS Journal of Surfaces and Colloids
Yuyi ShenMarjorie L Longo

Abstract

A low cost food grade emulsifier (a mixture of monoglycerides, diglycerides, and sodium stearoyl lactylate) in combination with polyethylene glycol-40 stearate (PEG-40S) was used as an alternative to pure saturated phospholipids to form the thin shell of a microbubble. To investigate the stability of these microbubbles in a water system over time, their dissolution behavior was studied at various degas factors and at two percentages of PEG-40S. It was found that the favored shell collapse/shedding mechanism switched, as the dissolution rate increased (degas factor decreased), from folding with a smooth surface contour to buckling accompanied by surface folding/expulsion with a cyclic buckled-smooth surface contour. The compositional change that we made played a more minor role, mainly controlling the resistance to mass transfer of the microbubble shell and again modifying the mechanism-determinant dissolution rate. The shell resistance behavior for these microbubbles varied from that of previous lipid/PEG-40S-coated microbubbles by the presence of a maximum in shell resistance during dissolution. We hypothesize that the dominance of one collapse mechanism over another for these compositions is related to the time scales of two ...Continue Reading

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Citations

Jun 29, 2018·Chemistry : a European Journal·Yifeng PengBrian D Polizzotti
Aug 27, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Monica M Lozano, Marjorie L Longo
Jun 29, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Benjamin L MicklavzinaMarjorie L Longo

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