Influence of the Menstrual Cycle on Blood Markers of Muscle Damage and Inflammation Following Eccentric Exercise

International Journal of Environmental Research and Public Health
Nuria Romero-ParraAna B Peinado

Abstract

The aim of this study was to evaluate whether the menstrual cycle and its underlying hormonal fluctuations affect muscle damage and inflammation in well-trained females following an eccentric exercise. Nineteen eumenorrheic women performed an eccentric squat-based exercise in the early follicular phase, late follicular phase and mid-luteal phase of their menstrual cycle. Sex hormones and blood markers of muscle damage and inflammation -creatine kinase, myoglobin, lactate dehydrogenase, interleukin-6, tumoral necrosis factor-, and C reactive protein- were analyzed in each phase. No effect of menstrual cycle phase was observed (p > 0.05), while an interaction for interleukin-6 was shown (p = 0.047). Accordingly, a moderate effect size [0.68 (0.53)-0.84 (0.74)], indicated that interleukin-6 values 2 h post-trial (2.07 1.26 pg/mL) were likely to be higher than baseline (1.59 0.33 pg/mL), 24 h (1.50 0.01 pg/mL) and 48 h (1.54 0.13 pg/mL) in the mid-luteal phase. Blood markers of muscle damage and inflammation were not affected by the menstrual cycle in well-trained women. The eccentric exercise barely triggered muscle damage and hence, no inflammation was observed, possibly due to participants training status. The mid-luteal phase w...Continue Reading

Associated Clinical Trials

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Citations

Dec 19, 2020·Journal of Strength and Conditioning Research·Nuria Romero-ParraUNKNOWN IronFEMME Study Group
Jan 28, 2021·International Journal of Environmental Research and Public Health·Beatriz RaelAna B Peinado
May 28, 2021·Sports Health·Nuria Romero-ParraAna B Peinado

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BETA
X-ray

Software Mentioned

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GE Encore 2002
SPSS

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