PMID: 1204230Nov 1, 1975Paper

Influence of the myopia gene on brain development

Clinical Genetics
J L Karlsson

Abstract

Evaluation of the performance of 17-18-year-old high school students on standard intelligence tests confirms previous reports that nearsighted persons consistently achieve scores approximately eight I.O. points higher than non-myopes. Comparison of tests administered to the same students 10 years earlier suggests that the intellectual gain precedes the development of nearsightedness. Since there is convincing evidence from genetic studies that myopia is an inherited condition, probably transmitted as a recessive characteristic, it is concluded that the myopia gene has a stimulant action on the brain in addition to its effect on the eye. The high frequency of myopia in urbanized societies is explained in terms of an evolutionary adjustment, myopes probably having a survival advantage under conditions of industrialization.

References

Mar 1, 1975·Clinical Genetics·J L Karlsson
Jan 1, 1974·Clinical Genetics·J I Karlsson
Jan 1, 1973·Hereditas·J L Karlsson
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May 1, 1970·American Journal of Optometry and Archives of American Academy of Optometry·T Grosvenor
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Sep 1, 1952·American Journal of Optometry and Archives of American Academy of Optometry·M J HIRSCH

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Citations

Dec 19, 1987·British Medical Journal·E Hare
Apr 1, 1985·Journal of Biosocial Science·G C Ashton
Feb 1, 1993·Journal of Epidemiology and Community Health·L WongC H Hwang
May 10, 2020·BMC Public Health·Jacob MegreliHagai Levine
Jan 1, 1986·Hereditas·J L Karlsson
Dec 1, 1981·Journal of Medical Genetics·J A Sofaer, A E Emery
Dec 1, 1988·Developmental Medicine and Child Neurology·S M WilliamsP A Silva
Feb 1, 1986·Perceptual and Motor Skills·R E Wharry, S W Kirkpatrick
Apr 7, 2017·Scientific Reports·Katie M WilliamsChristopher J Hammond
Nov 29, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Sunita ShankarWilliam R Bobier
Sep 1, 1988·Human Genetics·S J CohnA R Jensen
Apr 29, 2021·Investigative Ophthalmology & Visual Science·Ian G MorganJeremy A Guggenheim
Nov 24, 2004·Progress in Retinal and Eye Research·Ian Morgan, Kathryn Rose

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