PMID: 9449771Jan 1, 1996Paper

Influence of the postantibiotic effect and postantibiotic sub-MICs effect of netilmicin, tobramycin, ciprofloxacin and pefloxacin on alginate production by Pseudomonas aeruginosa

Folia Microbiologica
V Majtán, A Hostacká

Abstract

The postantibiotic effect (PAE) (postantibiotic phase induced by 2x or 4x MIC) as well as the postantibiotic effect of subinhibitory concentrations (0.1x, 0.2x and 0.3x MIC) (PA SME) of netilmicin, tobramycin, ciprofloxacin and pefloxacin affected the production of the virulence factor alginate by a P. aeruginosa strain. Aminoglycosides and ciprofloxacin at a concentration of 4x MIC inhibited the alginate production more significantly than 2x MIC. Suprainhibitory concentrations of aminoglycosides were more effective than pefloxacin (2x or 4x MIC) and ciprofloxacin (2x MIC). PA SME demonstrated by the above antibiotics (with the exception of ciprofloxacin 2x MIC + 0.1x MIC) suppressed alginate production more efficiently.

References

Feb 1, 1977·The Journal of Infectious Diseases·P J McDonaldC M Kunin
Jan 1, 1989·Antibiotics and Chemotherapy·N R Baker, C Svanborg-Edén
Apr 1, 1985·Canadian Journal of Microbiology·T I Nicas, B H Iglewski
Sep 1, 1968·Analytical Biochemistry·C A Knutson, A Jeanes
Jan 1, 1981·Reviews of Infectious Diseases·R W BundtzenW A Craig
Nov 1, 1981·The Journal of Antimicrobial Chemotherapy·A U Gerber, W A Craig
Dec 1, 1994·The Journal of Antimicrobial Chemotherapy·S GudmundssonW A Craig
Oct 1, 1993·The Journal of Antimicrobial Chemotherapy·F M MacKenzie, I M Gould
May 1, 1993·The Journal of Antimicrobial Chemotherapy·O Cars, I Odenholt-Tornqvist
Jun 1, 1993·The Journal of Antimicrobial Chemotherapy·I Odenholt-Tornqvist
Aug 1, 1993·Research in Nursing & Health·W K HahnD M Hartsough
May 1, 1993·Chemotherapy·M GottfredssonS Gudmundsson
Mar 1, 1996·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·A Hostacka
Oct 1, 1962·Analytical Biochemistry·T BITTER, H M MUIR

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.