PMID: 1083Jan 1, 1976

Influence of the products of phospholipolysis of phosphatidylcholine on micellar solubilization of fatty acids in the presence of bile salts

The British Journal of Nutrition
A K Lough, A Smith

Abstract

1. The solubility of fatty acids in aqueous solutions containing bile salts and lysolecithin at pH values between 2-0 and 7-4 was studied. Both the 1-acyl and 2-acyl isomers of lysolecithin increased the solubility of fatty acids to the same extent, the order of solubility being linoleic greater than oleic greater than elaidic greater than palmitic greater than stearic. 2. The influence of the products of phospholipolysis of lecithin on palmitic acid solubility was determined. On a molar basis, lysolecithin was more effective than were bile salts in promoting the solubilization of the fatty acid. 3. In bile salt solutions in which the phospholipid concentration was constant on a molar basis, in solubility of palmitic acid decreased linearly with the progressive replacement of lecithin by lysolecithin. Palmitic acid was solubilized to the same extent on replacing lecithin with lysolecithin on a constant weight basis. 4. In bile salt solution containing lysolecithin and oleic acid in equimolar amounts, the solubility of palmitic acid was similar to that in bile salt solution containing lecithin in equivalent proportion. 5. The results are discussed in relation to the action of phospholipolytic activity on the intestinal absorptio...Continue Reading

References

Jan 1, 1976·The British Journal of Nutrition·A Smith, A K Lough
Jan 1, 1975·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·G ArientiF A Harrison
Jul 7, 1972·Biochimica Et Biophysica Acta·D H Neiderhiser, H P Roth
Apr 1, 1969·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·W M Leat, F A Harrison
Mar 4, 1968·Biochimica Et Biophysica Acta·A Nilsson
May 1, 1968·The British Journal of Nutrition·A M LennoxG A Garton
May 1, 1968·The British Journal of Nutrition·A M Lennox, G A Garton
Jan 1, 1963·The British Journal of Nutrition·T J HEATH, B MORRIS

Citations

Jan 1, 1980·Journal of Dairy Science·D L Palmquist, T C Jenkins
Dec 1, 1993·Journal of Dairy Science·D Bauchart
Jul 1, 1984·Journal of Dairy Science·W ChalupaD Sklan

Related Concepts

Metazoa
Biliary Sludge
Bile Salts
Egg Food Product
Saturated Fat
Hydrogen-Ion Concentration
Hydrolysis
Isomerism
Lysophosphatidylcholines
Micelles

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