PMID: 1083Jan 1, 1976

Influence of the products of phospholipolysis of phosphatidylcholine on micellar solubilization of fatty acids in the presence of bile salts

The British Journal of Nutrition
A K Lough, A Smith


1. The solubility of fatty acids in aqueous solutions containing bile salts and lysolecithin at pH values between 2-0 and 7-4 was studied. Both the 1-acyl and 2-acyl isomers of lysolecithin increased the solubility of fatty acids to the same extent, the order of solubility being linoleic greater than oleic greater than elaidic greater than palmitic greater than stearic. 2. The influence of the products of phospholipolysis of lecithin on palmitic acid solubility was determined. On a molar basis, lysolecithin was more effective than were bile salts in promoting the solubilization of the fatty acid. 3. In bile salt solutions in which the phospholipid concentration was constant on a molar basis, in solubility of palmitic acid decreased linearly with the progressive replacement of lecithin by lysolecithin. Palmitic acid was solubilized to the same extent on replacing lecithin with lysolecithin on a constant weight basis. 4. In bile salt solution containing lysolecithin and oleic acid in equimolar amounts, the solubility of palmitic acid was similar to that in bile salt solution containing lecithin in equivalent proportion. 5. The results are discussed in relation to the action of phospholipolytic activity on the intestinal absorptio...Continue Reading


Jan 1, 1976·The British Journal of Nutrition·A Smith, A K Lough
Jan 1, 1975·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·G ArientiF A Harrison
Jul 7, 1972·Biochimica Et Biophysica Acta·D H Neiderhiser, H P Roth
Apr 1, 1969·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·W M Leat, F A Harrison
Mar 4, 1968·Biochimica Et Biophysica Acta·A Nilsson
May 1, 1968·The British Journal of Nutrition·A M LennoxG A Garton
May 1, 1968·The British Journal of Nutrition·A M Lennox, G A Garton
Jan 1, 1963·The British Journal of Nutrition·T J HEATH, B MORRIS


Jan 1, 1980·Journal of Dairy Science·D L Palmquist, T C Jenkins
Dec 1, 1993·Journal of Dairy Science·D Bauchart
Jul 1, 1984·Journal of Dairy Science·W ChalupaD Sklan

Related Concepts

Biliary Sludge
Bile Salts
Egg Food Product
Saturated Fat
Hydrogen-Ion Concentration

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.