PMID: 32677400Nov 1, 2018Paper

Influence of Ureaplasma Urealyticum Infection on Testicular Tissue Structure and Secretion Function in Rats

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Tao ZhangCong-Sen Liu

Abstract

To study the influences of ureaplasma urealitycum (UU) infection on testicular tissue structure and secretion function in rats. Forty clean grade male SD rats were randomly divided into the experiment group A (at 7 d after surgery), experiment group B (at 14 d after surgery), control group C (at 7 d after surgery) and control group D (at 14 d after surgery). There were 10 rats in each group. The experimental groups were injected with 0.6 mL UU4 through bladder. In the same way, the control groups were injected with the same volume of UU liquid medium. At day 7 and 14 after injection, the structures of testis of all rats were observed by light microscopy and spermatogenic cells by transmission electron microscopy. The content of testosterone in plasma and testicular fluid were detected by chemiluminescence method. The changes of inflammatory pathology (including the layer and amount of spermatogenic cell decreasing, inflammatory cell infiltrating and mature sperms decreasing) in the testis of group A and group B were found by light microscopy, and the inflammatory changes in group B were lighter than those in group A. The structures of testicular tissue in group C and group D were normal. The apoptosis performances of germ cell ...Continue Reading

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