PMID: 8964785Apr 1, 1996Paper

Influence of varying muscle forces on lumbar intradiscal pressure: an in vitro study

Journal of Biomechanics
H J WilkeA Wiesend

Abstract

The purposes of this study were to determine the effect of including muscle forces in the experimental loading of the spine on the intradiscal pressure and to determine whether this effect correlates with previously established in vivo data. We modeled the spine muscles as of five distinct groups and isolated the effect of each group on the intradiscal pressure (L4-L5). Seven human lumbosacral spines were tested in pure flexion/extension, right/left lateral bending, and left/right axial rotation moments. Stimulated muscle activity strongly influenced load-pressure characteristics, especially for the multifidus. Without muscle forces active, pressure increased proportionately with increasing moment. With five pairs of symmetrical constant muscle forces active (80 N per pair) the pressure increased more than 200% in neutral position and did not increase with increasing moment. The pressure without muscle forces and without axial preload was 0.12 MPa, which is about the same found by earlier in vivo studies of anesthetized subjects in prone position. With simulated muscle forces, the pressure was 0.39 MPa and in the range found for non-anesthetized subjects. We conclude that simulating muscle forces substantially affects intradisc...Continue Reading

References

Jan 1, 1987·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·A SchultzG Andersson
Jan 1, 1986·The Journal of Bone and Joint Surgery. British Volume·M A AdamsW C Hutton
Jan 1, 1967·Acta Orthopaedica Scandinavica·J O Galante
Jan 1, 1982·Journal of Biomechanics·A B SchultzR Björk
Jan 1, 1981·Spine·A L Nachemson
Jan 1, 1994·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·H J WilkeS Wolf
Jan 1, 1961·Anesthesia and Analgesia·G H LUCAS
Mar 1, 1993·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·M A AdamsA E Goodship
Nov 1, 1986·Clinical Biomechanics·J E Macintosh, N Bogduk
May 1, 1992·Clinical Biomechanics·N BogdukG Hadfield

❮ Previous
Next ❯

Citations

Jan 24, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·El-hadi SariAliWaffa Skalli
Jan 24, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·W SchmoelzH J Wilke
Feb 19, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Sarit Sara SivanAlice Maroudas
Jan 5, 2000·Clinical Biomechanics·P BernhardtL E Claes
Nov 21, 2009·Computer Methods in Biomechanics and Biomedical Engineering·Hun Guan ChuahMohd Imran Yusof
Jan 11, 2008·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Craig RansonRobert Kerslake
Sep 1, 2007·Journal of Biomechanics·Christopher R DennisonDavid R Wilson
Aug 25, 2015·Frontiers in Bioengineering and Biotechnology·Themis Toumanidou, Jérôme Noailly
Dec 4, 2013·The Spine Journal : Official Journal of the North American Spine Society·James J DoulgerisFrank D Vrionis
Jul 28, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Maryse FortinMichele C Battié
Jul 7, 2020·Frontiers in Bioengineering and Biotechnology·Hans-Joachim WilkeChristian Liebsch
Jan 25, 2003·Spine·Kyle E SwansonScott A Yerby
Sep 18, 2020·Biomechanics and Modeling in Mechanobiology·Robert RockenfellerKarin Gruber
Feb 5, 1999·Neurosurgery·J PospiechL E Claes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.