Influence of vitamin C on bisphenol A, nonylphenol and octylphenol induced oxidative damages in liver of male rats

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Asli KorkmazNurhayat Barlas

Abstract

The purpose of this study was to investigate whether bisphenol A (BPA), nonylphenol (NP) and octylphenol (OP) induce oxidative stress in the liver of male rats and co-administration of vitamin C can prevent any possible oxidative stress. Wistar male rats were divided into seven groups (vehicle, BPA, NP, OP, BPA+C, NP+C, OP+C). BPA, OP and NP groups (25 mg kg(-1)day(-1)) were administered orally to rats three times a week for 50 days. In BPA+C, NP+C, OP+C groups, vitamin C (60 mg kg(-1)day(-1)) was administered along with BPA, OP and NP (25 mg kg(-1)day(-1)) treatments. Aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH), thiobarbituric acid-reactive substances (TBARS) were increased, glutathione (GSH) levels were decreased in treatment groups. AST, ALT, LDH and TBARS levels were increased whereas GSH levels were decreased in BPA+C, NP+C and OP+C groups compared to BPA, NP, and OP groups, respectively. Hepatic necrosis and congestion were observed in livers of rats treated. In conclusion, the present results demonstrate that BPA, NP, and OP cause oxidative damage by disturbing the balance between ROS and antioxidant defenses system in liver of male rats. Vitamin C co-administration along with BP...Continue Reading

References

Nov 17, 1992·Biochemical Pharmacology·A Meister
Apr 1, 1990·Archives of Biochemistry and Biophysics·D C Laudicina, L J Marnett
Jan 1, 1995·Environmental and Molecular Mutagenesis·A Atkinson, D Roy
Jul 1, 1994·Endocrinology·R WhiteM G Parker
Sep 27, 1996·Biochemical Pharmacology·P C LeeM Struve
Jan 1, 1996·Journal of the American Optometric Association·E Cheraskin
Jan 1, 1996·Annual Review of Nutrition·B Halliwell
Aug 1, 1996·Environmental Health Perspectives·J ToppariN E Skakkebaek
Jan 1, 1996·Archives of Toxicology·H CertaH M Bolt
Feb 1, 1997·Journal of Ethnopharmacology·A T Mobarok Ali, O A al-Swayeh
Jan 1, 1997·Free Radical Biology & Medicine·G BánhegyiJ Mandl
Oct 28, 1998·Environmental Health Perspectives·Y S HoJ Cao
Jun 5, 1999·The American Journal of Clinical Nutrition·A C Carr, B Frei
Mar 8, 2000·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·L M AntunesM D Bianchi
Apr 4, 2000·Toxicological Sciences : an Official Journal of the Society of Toxicology·S C LawsR L Cooper
Oct 29, 2000·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·M OrellanaV Guajardo
May 22, 2001·Archives of Biochemistry and Biophysics·A J Young, G M Lowe
Sep 21, 2002·Archives of Toxicology·K C ChitraP P Mathur
Jul 17, 2003·Environmental Research·H KabutoT Shishibori
Jun 24, 2004·Aquatic Toxicology·Linda HasselbergAsbjørn Svardal
Sep 25, 2004·Bulletin of Environmental Contamination and Toxicology·X HanY Hou
Dec 6, 2005·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Asli Doğan, Dürdane Kolankaya
Mar 8, 2006·Reproductive Toxicology·Müfide Aydoğan, Nurhayat Barlas
Apr 25, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Qian BianXinru Wang
Aug 9, 2007·Reproductive Toxicology·Catherine A RichterFrederick S vom Saal
Dec 2, 2008·Toxicology·Hina RashidSheikh Raisuddin
Jul 1, 2002·Environmental Toxicology and Pharmacology·Ivonne M C M RietjensJan H Koeman

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Citations

Feb 23, 2011·International Journal of Molecular Sciences·Zhen MaoYan-Qiu Zhang
Nov 29, 2013·Journal of Epidemiology and Community Health·Mee-Ri LeeYun-Chul Hong
Aug 14, 2012·Oxidative Medicine and Cellular Longevity·Zeinab K HassanEbtisam M AlOlayan
Jun 2, 2015·Pakistan Journal of Biological Sciences : PJBS·Wessam Mohamad Abdel-Wahab
Jul 11, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Shalini SagguHasibur Rehman
Oct 31, 2015·Free Radical Research·Pei-Wei WangYu-Fang Huang
Feb 7, 2012·Regulatory Toxicology and Pharmacology : RTP·R JubendradassP P Mathur
Jul 19, 2012·Clinical Endocrinology·Giovanni TarantinoSilvia Savastano
Aug 16, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Sameya AnjumSheikh Raisuddin
Jun 18, 2016·Systems Biology in Reproductive Medicine·Jian WangXiaoying Zhang
Sep 4, 2016·Biochemical and Biophysical Research Communications·Sohrab KazemiAli Akbar Moghadamnia
Feb 9, 2017·Journal of Pineal Research·Mianqun ZhangBo Xiong
Feb 16, 2018·Environmental Science and Pollution Research International·Qudsia KanwalBushra Munir
Feb 2, 2018·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·T OzaydınM O Dayan
Feb 14, 2019·Environmental Science and Pollution Research International·Ahmet BilgiAhmet Birtan Boran
Sep 30, 2015·Cytotechnology·Burak Kaptaner
Dec 2, 2017·Oncotarget·Bin LiuYuping Gao
Sep 13, 2018·Mini Reviews in Medicinal Chemistry·Xun Zhang, Rutao Liu
Jul 30, 2020·Biomolecules·Shehreen AmjadMyung-Geol Pang
Apr 30, 2017·Experimental and Therapeutic Medicine·Mihaela ZauletAnca Hermenean
Aug 28, 2018·Oxidative Medicine and Cellular Longevity·Haidy G Abdel-RahmanAaser M Abdelazim
Apr 23, 2020·International Journal of Environmental Research and Public Health·Jin Hee Kim, Yun-Chul Hong
Aug 8, 2019·Environmental Science and Pollution Research International·Samuel Gbadebo OlukoleBankole Olusiji Oke
Dec 20, 2019·Experimental and Therapeutic Medicine·Saber M EwedaAssmaa S Gaber
Nov 15, 2011·Human & Experimental Toxicology·R JubendradassP P Mathur
Jul 4, 2013·Human & Experimental Toxicology·N Yıldız, N Barlas
Nov 6, 2017·Environmental Science and Pollution Research International·Maurya KhushbooGuruswami Gurusubramanian
Apr 14, 2017·International Journal of Toxicology·Dinesh Tiwari, Geeta Vanage
Nov 30, 2018·International Journal of Environmental Research and Public Health·Kun ZhouYankai Xia

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