Influence of volume preloading on uteroplacental and fetal circulation during spinal anaesthesia for caesarean section in uncomplicated singleton pregnancies

Fetal Diagnosis and Therapy
Sevgi TercanliWolfgang Holzgreve

Abstract

Effects of volume preloading during spinal anaesthesia for elective caesarean section on maternal blood pressure, feto-maternal circulation and fetal outcome. In a pilot study a randomised trial was performed in 22 healthy women with uncomplicated, singleton pregnancies at 36-40 weeks of gestation undergoing elective caesarean section under spinal anaesthesia. In the low volume group (group A) patients received 150 ml of crystalloid solution for preloading, in the high volume group (group B) they were given 15 ml/kg of crystalloid solution for preloading before the initiation of spinal anaesthesia. Maternal blood pressure was monitored intermittently. Hypotension was defined as a decrease in systolic pressure to less than 80% of the baseline value. The Doppler flow evaluation consisted of measurements from the uterine artery at the placental site, fetal umbilical artery and fetal middle cerebral artery. Pulsatility indices were derived before and after fluid preloading, and when spinal anaesthesia was established. The neonatal outcome was assessed by Apgar scores, arterial acid base status and neurologic and adaptive capacity scores (NACS). The incidence of maternal hypotension in both groups was 45.5% (n = 10); 3 cases occurre...Continue Reading

Citations

Sep 14, 2002·Prenatal Diagnosis
Jan 24, 2004·Archives of Gynecology and Obstetrics·Sayaka Okudaira, Shunji Suzuki
Apr 25, 2012·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Christian Loubert
Jul 28, 2012·International Journal of Critical Illness and Injury Science·Sukhminder Jit Singh BajwaSurjit Singh Parmar
Jan 14, 2018·Archives of Gynecology and Obstetrics·K LatoU Friebe-Hoffmann
May 7, 2008·Current Opinion in Anaesthesiology·Eva Roofthooft, Marc Van de Velde
Feb 13, 2019·Current Opinion in Anaesthesiology·Marc Van de Velde
Oct 5, 2017·The Cochrane Database of Systematic Reviews·Cheryl ChooiAllan M Cyna
Jul 4, 2020·The Cochrane Database of Systematic Reviews·Cheryl ChooiAllan M Cyna
Apr 5, 2016·European Journal of Anaesthesiology·Gernot MarxMichaela Eikermann

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