PMID: 9654553Jul 9, 1998Paper

Influence of water immersion stress on peripheral nerve recovery in the rat

Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association
M Amako, K Nemoto

Abstract

An experimental study was performed to investigate the relationship between stress and peripheral nerve recovery. Male Wistar rats weighing 200-250 g were used. The sciatic nerve was crushed unilaterally with an aneurysm clip. Stress was applied by water immersion for 3 h, three times a week, from 1 week preoperatively, and continued for 6 or 8 weeks. The animals' walking tracks were measured every week to evaluate nerve function, and a sciatic functional index (SFI) was calculated. Specimens for histological examination were taken from the nerve at a site distal to the crush injury. By 3 weeks postoperatively, the SFI in the non-stress groups had recovered, but it remained at significantly lower levels in the stress groups (P < 0.01). Histological studies showed that the recovery of nerve fibers was retarded and regenerating axons were smaller in the stress groups. Peripheral nerve recovery after crush injury was suppressed by water-immersion stress.

References

Mar 1, 1975·The American Journal of Digestive Diseases·W P Paré
Mar 1, 1994·Digestive Diseases and Sciences·P ZacchiJ R Malagelada
Jul 1, 1993·Journal of Reconstructive Microsurgery·L E ChenJ R Urbaniak

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.