PMID: 15376568Sep 21, 2004Paper

Influenza-A as etiology of fever and respiratory insufficiency in adults hospitalized during an outbreak in Chile

Revista médica de Chile
Ricardo RabagliatiJaime Labarca

Abstract

Influenza-A (IA) occurs every winter, is mostly observed among outpatients. To describe the clinical and epidemiological characteristics of cases that required hospital admission during an outbreak in Chile in 1999. Adults subjects, with Influenza A confirmed by antigen detection test, hospitalized in the clinical hospital of the "Hospital Clínico de la Universidad Católica de Chile" between May and June, with fever or respiratory symptoms were studied. A special record was designed to register clinical, microbiological and therapeutic data. Fifty five cases, 26 males, aged 15 to 91 years, were studied. Eighty four percent had chronic concomitant diseases and 9.1% were immunosuppressed. Clinical findings were fever in 873%, asthenia in 83.6%, cough in 93.6%, abnormal pulmonary signs in 69%, an elevated C-reactive protein (mean value of 11.6 +/- 7.1 mg/dL) and acute respiratory insufficiency in 54.5%. Cases were isolated in cohort or individual rooms and 38.2% were admitted to intensive or intermediate care units. Amantadine was prescribed to 52 patients and was well tolerated. Thirty three percent of cases developed pneumonia. These subjects were older; had more dyspnea and respiratory insufficiency than patients without pneumo...Continue Reading

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