Influenza A (H1N1) virus-induced hepatocellular injury in a kidney transplant patient

Transplant Infectious Disease : an Official Journal of the Transplantation Society
M DaudéN Kamar

Abstract

The swine-origin influenza A (H1N1) virus is mainly responsible for flu. No hepatitis attributable to H1N1 virus has been previously documented. Herein, we report on a kidney transplant patient who developed influenza H1N1 virus-induced hepatocellular injury. The patient's body temperature was only somewhat elevated, and pulmonary and flu symptoms were mild. H1N1 virus was detected by polymerase chain reaction assay in nasopharyngeal and bronchoalveolar swabs, as well as in the serum. The hepatocellular injury episode resolved after the patient had been placed on oseltamivir therapy. This observation suggests that acute hepatocellular injury could be linked to the influenza H1N1 virus.

References

Mar 28, 2006·The American Journal of Pathology·Noelle K PolakosRobert H Pierce
Jun 16, 2009·Nature·Gabriele NeumannYoshihiro Kawaoka
Jul 1, 2009·The New England Journal of Medicine·Rogelio Perez-PadillaUNKNOWN INER Working Group on Influenza
Oct 14, 2009·JAMA : the Journal of the American Medical Association·Guillermo Domínguez-CheritRobert A Fowler

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Citations

Jul 23, 2015·Hemodialysis International·Maggie Ming Yee MokWai Kei Lo

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