Abstract
Recently, the World Health Organization declared a pandemic mediated by the novel A H1N1 influenza virus. Soon after the first report from Mexico, the disease arrived in Chile, where it spread quickly from south to north, mimicking cold weather progression through the country. Between May and September 2009, 366,624 cases of H1N1 were reported; 12,248 were confirmed by real-time reverse-transcription polymerase chain reaction and 1562 were hospitalized. One hundred thirty-two deaths were attributable to the infection, creating a death rate of 0.78 per 100,000 inhabitants. Common comorbidities were present in 59%, including obesity, chronic obstructive pulmonary disease, hypertension, type II diabetes, and congestive heart failure. Nine percent were pregnant. Severe disease developed early; the median time to admittance was 5 days, and the most common clinical manifestations were cough, fever, dyspnea, and myalgia. Mean acute physiology and chronic health evaluation II and sequential organ failure assessment scores were 14 and 5, respectively. Highlighted laboratory data were lactate dehydrogenase and creatine kinase elevation, leukocytosis in 50%, elevated creatinine in a 25%, and thrombocytopenia in 20%. Severe respiratory fai...Continue Reading
Citations
Mar 12, 2011·Intensive Care Medicine·N NinA Esteban
Aug 24, 2011·Obstetrics and Gynecology·Michael W VarnerUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Networ
Apr 19, 2012·Critical Care Medicine·Todd W RiceUNKNOWN NHLBI ARDS Network
Jun 1, 2011·American Journal of Nephrology·Sevag G DemirjianJorge A Guzman
Mar 6, 2010·American Journal of Respiratory and Critical Care Medicine·Elisa EstenssoroUNKNOWN Registry of the Argentinian Society of Intensive Care SATI
Jun 2, 2010·BMC Infectious Diseases·Wei CuiPei Liu
Nov 15, 2012·BMC Infectious Diseases·Gerardo ChowellAndrea Olea
Aug 19, 2011·Critical Care : the Official Journal of the Critical Care Forum·Fernando G RíosGuillermo Chiappero
Dec 23, 2011·Critical Care : the Official Journal of the Critical Care Forum·Luciano GattinoniThomas Langer
Apr 17, 2012·PloS One·Ana M BalanzatMarc-Alain Widdowson
Jul 31, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Regina C R M AbdulkaderLúcia Andrade
Aug 2, 2011·Emerging Infectious Diseases·Kate A WardJeremy M McAnulty
May 5, 2012·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Mohan GurjarA K Baronia
Feb 11, 2015·Global Heart·William A FischerJonathan Sevransky
Oct 16, 2010·Wiener klinische Wochenschrift·Walter R HasibederGabriele Brinninger
Feb 15, 2011·Wiener klinische Wochenschrift·Tacettin OrnekMücahit Yemişen
Oct 16, 2012·European Journal of Pediatrics·Toru Watanabe
Aug 14, 2012·Infection·S BauernfeindB Salzberger
Aug 31, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Yong Bum ParkUNKNOWN Korean Asthma Study Group
Feb 22, 2012·Medicina intensiva·J BonastreUNKNOWN SEMICYUC-CIBERES-REIPI working group
Aug 16, 2011·The Journal of Infection·Anika SinganayagamJames D Chalmers
Apr 15, 2011·Journal of Critical Care·Ji Ye JungMoo Suk Park
Feb 9, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·G DubarA Mignon
Feb 18, 2012·Influenza and Other Respiratory Viruses·Erik A KarlssonStacey Schultz-Cherry
Jun 15, 2011·Influenza and Other Respiratory Viruses·Maria D Van KerkhoveUNKNOWN WHO Southern Hemisphere Influenza Comparison Study Working Group
Nov 19, 2011·Acta Anaesthesiologica Scandinavica·R LinkoUNKNOWN FINNH1N1-STUDY GROUP
Aug 21, 2013·Influenza and Other Respiratory Viruses·Noelle M CocorosMichael Klompas
Feb 25, 2011·American Journal of Obstetrics and Gynecology·Laura G MosbyDenise J Jamieson
Jan 24, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J M PereiraUNKNOWN ESICM H1N1 Registry Contributors
Jan 26, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Tanil KendirliErdal Ince
Jan 26, 2011·Critical Care Medicine·Enrique Maraví-PomaUNKNOWN Grupo Español de Trabajo de Gripe Grave A (SEMICYUC)
Dec 6, 2018·Influenza and Other Respiratory Viruses·Joe-Ann S MoserUNKNOWN La Red ILI 002 Study Group
Dec 12, 2018·BMC Infectious Diseases·Chandini Raina MacIntyreAnita Heywood
Apr 24, 2021·American Journal of Respiratory and Critical Care Medicine·Pineton de ChambrunAlain Combes