Influenza A viruses: new research developments

Nature Reviews. Microbiology
Rafael A Medina, Adolfo García-Sastre

Abstract

Influenza A viruses are zoonotic pathogens that continuously circulate and change in several animal hosts, including birds, pigs, horses and humans. The emergence of novel virus strains that are capable of causing human epidemics or pandemics is a serious possibility. Here, we discuss the value of surveillance and characterization of naturally occurring influenza viruses, and review the impact that new developments in the laboratory have had on our understanding of the host tropism and virulence of viruses. We also revise the lessons that have been learnt from the pandemic viruses of the past 100 years.

References

Dec 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·G M Air
Sep 18, 1999·Lancet·M PeirisK F Shortridge
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·Y P LinA Hay
Mar 5, 2002·Bulletin of the History of Medicine·Niall P A S Johnson, Juergen Mueller
Aug 27, 2002·Nature Medicine·Sang Heui SeoRobert G Webster
Jan 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ron A M FouchierAlbert D M E Osterhaus
Feb 15, 2005·Journal of Virology·Ron A M FouchierAlbert D M E Osterhaus
Sep 30, 2005·The New England Journal of Medicine·John H BeigelUNKNOWN Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5
Oct 8, 2005·Science·Terrence M TumpeyAdolfo García-Sastre
Oct 18, 2005·Nature·Q Mai LeYoshihiro Kawaoka
Dec 2, 2005·Emerging Infectious Diseases·Vincent J MunsterRon A M Fouchier
Dec 13, 2005·Proceedings of the National Academy of Sciences of the United States of America·G GabrielJ Stech
Jan 28, 2006·Science·John C ObenauerClayton W Naeve
Feb 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·H ChenY Guan
Mar 15, 2006·The Journal of Experimental Medicine·Rachelle SalomonErich Hoffmann
Mar 24, 2006·Nature·Kyoko ShinyaYoshihiro Kawaoka
Mar 25, 2006·Science·Debby van RielThijs Kuiken
Apr 1, 2006·Glycoconjugate Journal·R J RussellJ J Skehel
Apr 22, 2006·Science·Thijs KuikenBryan T Grenfell
Jun 16, 2006·Journal of Virology·Ana Fernandez-SesmaThomas M Moran
Aug 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·Taronna R MainesJacqueline M Katz
Nov 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·G J D SmithY Guan
Dec 5, 2006·PLoS Pathogens·Martha I NelsonEdward C Holmes
Jan 9, 2007·Nature Medicine·J M NichollsJ S M Peiris
Jun 5, 2007·Vaccine·Noelle-Angelique M MolinariCarolyn B Bridges
Jul 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Rachelle SalomonRobert G Webster

❮ Previous
Next ❯

Citations

Jan 18, 2013·Virologica Sinica·Jingchuan YinYing Zhu
Jul 9, 2013·Antiviral Research·David S Fedson
Apr 24, 2013·Journal of Theoretical Biology·Lisa N MurilloAlan S Perelson
Jun 6, 2013·Virus Research·Stephanie SonnbergRobert G Webster
Aug 13, 2013·Nature Biotechnology·Ryan A LangloisBenjamin R tenOever
Feb 22, 2012·Nature Immunology·Nan Yan, Zhijian J Chen
Sep 29, 2012·Proceedings of the National Academy of Sciences of the United States of America·Philippe Noriel Q PascuaYoung-Ki Choi
Sep 27, 2012·Proceedings of the National Academy of Sciences of the United States of America·Qing LiGeorge F Gao
Oct 27, 2012·Proceedings of the National Academy of Sciences of the United States of America·Adolfo García-Sastre
Nov 15, 2012·The Journal of Biological Chemistry·Diogo V da SilvaRobert Daniels
Aug 1, 2013·The Journal of Infectious Diseases·Chih-Heng HuangShin-Ru Shih
Jan 10, 2012·Transboundary and Emerging Diseases·M TorremorellM Gramer
Aug 30, 2013·Science Translational Medicine·Surender KhuranaHana Golding
Apr 12, 2012·Clinical Microbiology Reviews·Joachim Denner, Ralf R Tönjes
Jan 4, 2013·Journal of Virology·Christopher B BrookeJonathan W Yewdell
Sep 15, 2012·BMC Medicine·Sailen Barik
Jul 5, 2013·PLoS Pathogens·Pei-Ling TsaiBeatriz M A Fontoura
Feb 14, 2013·Avian Diseases·Susan C TrockNancy J Cox
Apr 3, 2014·Avian Diseases·Jennifer M MadsenNathaniel L Tablante
Jan 25, 2013·Viruses·Irene Ramos, Ana Fernandez-Sesma
Aug 9, 2012·Journal of Molecular and Genetic Medicine : an International Journal of Biomedical Research·Lane VotapkaRommie E Amaro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.