Influenza and the challenge for immunology

Nature Immunology
Peter C DohertyPaul G Thomas

Abstract

The continued westward dissemination of H5N1 influenza A viruses in avian populations and the nearly 50% mortality rate of humans infected with H5N1 are a source of great international concern. A mutant H5N1 virus with the capability to spread rapidly between humans could cause a global catastrophe. Governments have reacted by developing national response plans, stockpiling antiviral drugs and speeding up the development and approval of vaccines. Here we summarize what is known about the interaction between influenza A viruses and the mammalian host response, specifically emphasizing issues that might be of interest to the broader immunology community.

References

Oct 1, 1996·Current Opinion in Structural Biology·M von Itzstein, P Colman
Jan 7, 1998·Immunological Reviews·P C DohertyP G Stevenson
Jan 9, 1999·Journal of Virology·J M RiberdyP C Doherty
Jul 21, 1999·Proceedings of the National Academy of Sciences of the United States of America·K J FlynnP C Doherty
Aug 4, 1999·Proceedings of the National Academy of Sciences of the United States of America·P G StevensonP C Doherty
Jun 3, 2000·Annual Review of Immunology·P C Doherty, J P Christensen
Mar 20, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·G T BelzP C Doherty
May 10, 2001·Proceedings of the National Academy of Sciences of the United States of America·D R MarshallP C Doherty
Aug 18, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·S J TurnerP C Doherty
Aug 7, 2002·Vaccine·Erich HoffmannRobert G Webster
Aug 27, 2002·Nature Medicine·Sang Heui SeoRobert G Webster
Feb 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Barbara J JohnsonAnne Kelso
May 31, 2003·Proceedings of the National Academy of Sciences of the United States of America·Richard J WebbyStephen J Turner
Jun 13, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David S Fedson
Sep 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Julia R GogBryan T Grenfell
Jan 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ron A M FouchierAlbert D M E Osterhaus
Feb 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Gabrielle T BelzWilliam R Heath
Feb 21, 2004·Science·Sandra S DieboldCaetano Reis e Sousa
Mar 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Stephen J TurnerPeter C Doherty
Mar 24, 2004·Proceedings of the National Academy of Sciences of the United States of America·Katherine KedzierskaPeter C Doherty
Apr 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Nicole L La GrutaPeter C Doherty
May 28, 2004·Virus Research·W FiersW Min Jou
May 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Gabrielle T BelzWilliam R Heath

❮ Previous
Next ❯

Citations

Mar 4, 2009·Pharmaceutical Research·Barbara C BaudnerDerek T O'Hagan
Apr 14, 2010·Pharmaceutical Research·Yeu-Chun KimMark R Prausnitz
Jun 12, 2012·Virologica Sinica·Ma-ping DengFei Deng
Apr 13, 2011·Immunology and Cell Biology·Michelle D TateJustine D Mintern
Feb 13, 2013·Immunology and Cell Biology·Emma GrantWeisan Chen
Feb 9, 2012·Nature Medicine·Anne Kelso
Jan 5, 2007·Nature Reviews. Microbiology·Kevin K AriënEric J Arts
Jan 17, 2008·Nature Reviews. Microbiology·Gunilla B Karlsson HedestamRichard T Wyatt
Jan 11, 2007·Immunology and Cell Biology·Nicole L La GrutaPeter C Doherty
Dec 3, 2008·Proceedings of the National Academy of Sciences of the United States of America·Katherine KedzierskaStephen J Turner
Feb 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·Grazia GalliFlora Castellino
Aug 8, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jin Hyang KimJoshy Jacob
Sep 24, 2008·The Journal of Experimental Medicine·Hailong GuoSubramaniam Malarkannan
Jun 16, 2010·The Journal of Experimental Medicine·Jae-Kwang YooEleanor N Fish
Aug 23, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·N LeeJ J Y Sung
May 15, 2008·Viral Immunology·David VerhoevenDonna L Farber
Jul 3, 2007·Viral Immunology·Maryna C Eichelberger
Nov 6, 2007·Nucleic Acids Research·In Seok YangKyung Hyun Kim
Jan 1, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Raoul E NapTjip S van der Werf
Apr 12, 2007·Journal of the Royal Society, Interface·Marc Lipsitch, Justin J O'Hagan
Jul 5, 2007·Journal of the Royal Society, Interface·Florence DébarreRoland R Regoes
May 29, 2009·Journal of the Royal Society, Interface·Andreas HandelRustom Antia
May 24, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·Alan C-Y HsuPeter A B Wark
Mar 15, 2013·Science Translational Medicine·Salah-Eddine BentebibelHideki Ueno
Sep 9, 2011·Clinical and Vaccine Immunology : CVI·Anna J X ZhangKwok-Yung Yuen
Sep 28, 2012·Journal of Virology·Timothy J PowellAlain R M Townsend
Mar 26, 2010·Journal of Virology·Risa NakamuraYasunobu Yoshikai
Jul 17, 2008·Respiratory Research·Rosa C GualanoGary P Anderson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Emerging Infectious Diseases
Paul G ThomasPeter C Doherty
Proceedings of the National Academy of Sciences of the United States of America
Katherine KedzierskaPeter C Doherty
© 2022 Meta ULC. All rights reserved