Influenza-attributable mortality in Australians aged more than 50 years: a comparison of different modelling approaches

Epidemiology and Infection
Anthony T NewallJames G Wood

Abstract

This study aimed to compare systematically approaches to estimating influenza-attributable mortality in older Australians. Using monthly age-specific death data together with viral surveillance counts for influenza and respiratory syncytial virus, we explored two of the most frequently used methods of estimating excess influenza-attributable disease: Poisson and Serfling regression models. These approaches produced consistent age and temporal patterns in estimates of influenza-attributable mortality in older Australians but some variation in the magnitude of the disease burden. Of Australians aged >50 years, average annual estimated influenza-attributable deaths (all cause) ranged from 2314 to 3457 for the Serfling and Poisson regression models, respectively. The excess influenza-attributable disease burden was substantial under all approaches.

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Oct 9, 2012·Epidemiology and Infection·F T M FreitasW N Araujo
Dec 20, 2011·BMC Infectious Diseases·Jens NielsenKåre Mølbak
Jun 30, 2012·PloS One·Xi-Ling WangChit-Ming Wong
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Sep 25, 2017·Pediatrics International : Official Journal of the Japan Pediatric Society·Suji KimHyunju Lee
Jul 14, 2012·PharmacoEconomics·Anthony T NewallPhilippe Beutels
Apr 29, 2020·Human Vaccines & Immunotherapeutics·Li QiQi-Yong Liu
Dec 3, 2017·Influenza and Other Respiratory Viruses·Desmond GulDavid J Muscatello
Aug 2, 2021·International Journal of Epidemiology·Vivian K Y LeungSheena G Sullivan

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