Influenza in pediatric intensive cure unit

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
N RichardD Floret

Abstract

The purpose was to identify clinical presentation leading to admission to PICU of children affected by influenza, to describe predisposing factors and outcome and to propose preventive measures. Ten years (1989-1999) retrospective study carried out in the ten beds PICU. Every child in PICU with an influenza positive culture was enrolled. Twenty four cases collected, aged two weeks-15 years (m =43 months), 19 males. Acute respiratory failure (16/24 =67%) was the first manifestation: pneumonia (13), bronchiolitis (2), status asthmaticus (1). Eleven children had underlying diseases including five immunocompromized. Thirteen patients required mechanical ventilation (mean duration: 22 days), seven developed ARDS (4 immunocompromized) and three died. Central nervous system was the second system affected (8 cases). Four exhibited a chronical cerebral disease and five presented afebrile status epilepticus which required i.v. barbiturates and mechanical ventilation (mean duration: 22 hours). One presented encephalitis, one an apparent life-threatening event, both had a favorable outcome. One child exhibited severe hyperpyrexia and died from multiorgan failure. Severe forms of influenza are rare in children but may lead to life-threateni...Continue Reading

Citations

Jan 27, 2010·Critical Care Medicine·Robert A FowlerJohn C Marshall
Jan 30, 2007·The Pediatric Infectious Disease Journal·Dominique PloinDaniel Floret
Oct 1, 2010·Indian Journal of Pediatrics·Kam Lun HonPaul Kay Sheung Chan
Jun 3, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michael W QuasneyUNKNOWN Pediatric Acute Lung Injury Consensus Conference Group

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