Influenza surveillance in Zambia, 2008-2009

The Journal of Infectious Diseases
Andros TheoMwaka Monze

Abstract

Limited information exists about influenza viruses in Africa. We used data from a new sentinel surveillance system to investigate the seasonality and characteristics of influenza, including pandemic (pdm) influenza A H1N1, in Zambia. In June 2008, we established sentinel surveillance for influenza-like illness (ILI) and severe acute respiratory illness (SARI) at 4 healthcare facilities in Zambia. Nasopharyngeal and oropharyngeal swabs and structured questionnaires were collected from eligible patients and samples were tested by real-time reverse-transcription polymerase chain reaction for influenza virus types and subtypes. From June 2008 to December 2009, we collected 1234 specimens, of which 334 (27%) were ILI, and 900 (63%) were SARI. Overall, 4% (57) of specimens were positive for influenza. The influenza detection rate in ILI and SARI cases was 5% (17/334) and 4% (40/900), respectively. Among all influenza cases, 54 (95%) were influenza A and 3 (5%) were influenza B. Of the influenza A viruses, 16 (30%) were A(H1N1)pdm09, 29 (54%) were seasonal A(H1N1), 6 (11%) were A(H3N2), and 4 (7%) were unsubtyped. The detection rate for A(H1N1)pdm09 cases was highest in persons aged 5-24 years (5/98; 5%), 25-44 years (4/78; 5%), and 4...Continue Reading

References

May 9, 2009·The New England Journal of Medicine·Fatimah S DawoodTimothy M Uyeki
Aug 4, 2009·The Medical Journal of Australia·Heath A KellyDavid Smith
May 27, 2010·JAMA : the Journal of the American Medical Association·James A BerkleyD James Nokes
Mar 5, 2011·The Lancet Infectious Diseases·Bradford D GessnerSylvie Briand
May 4, 2011·Journal of Infection in Developing Countries·Amal BarakatSylvie Van der Werf

Citations

Sep 11, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E M MpabalwaniFernanda C Lessa
Dec 16, 2017·Influenza and Other Respiratory Viruses·Andros TheoMwaka Monze
Jan 5, 2020·Infectious Diseases of Poverty·Zhi-Wei XuWen-Biao Hu
Jan 15, 2020·BMC Health Services Research·Paul SimusikaMwaka Monze
Oct 10, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Edgar SimulunduNathan Kapata

Related Concepts

Disease Outbreaks
Influenza
Influenza B virus
Seasonal Variation
Sentinel Surveillance
Reverse Transcriptase Polymerase Chain Reaction
Severe Acute Respiratory Syndrome
Influenza A Virus, H1N1 Subtype
Pandemics
Epidemiology

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