PMID: 6987929Apr 1, 1980Paper

Influenza vaccination in kidney transplant recipients: cellular and humoral immune responses

Annals of Internal Medicine
W A BriggsF D McDonald

Abstract

Influenza infection in renal transplant recipients may cause either morbidity and mortality or acute allograft rejection; thus, routine annual influenza vaccination should be considered. We have studied the humoral and cellular immune responses to influenza virus antigens before and after trivalent vaccine administration in 13 patients and 16 control subjects. The patients, nine of whom were either on alternate-day or low-dose daily steroid therapy, showed highly significant serum hemagglutination-inhibition antibody responses to each influenza virus strain, There was no significant change in mean lymphocyte stimulation index to any influenza virus strain after vaccination in either group. There was no correlation in the patient group between hemagglutination-inhibition antibody titer or response, or lymphocyte stimulation index or response, and the degree of allograft function or dose or duration of immunosuppressive therapy. The vigorous antibody response and the evidence of cellular immunity support the efficacy of influenza vaccination in these patients.

Citations

Nov 1, 1996·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·D R MackT G Heffron
Oct 20, 2009·Der Nervenarzt·M LöbermannU K Zettl
Mar 17, 1997·The American Journal of Medicine·F G Hayden
Jan 1, 1985·Antiviral Research·D J VersluisW Weimar
May 18, 1999·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·S FraundA Haverich
Jun 5, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R K Avery, P Ljungman
Feb 25, 2010·Transplantation·Lara Danziger-IsakovEmilio D Poggio
Jul 15, 2003·Clinical Microbiology Reviews·Andrea DuchiniPaul J Pockros
Aug 22, 2012·American Journal of Nephrology·Kelly A BirdwellT Alp Ikizler
Feb 5, 2014·Immunotherapy·Delphine Zbinden, Oriol Manuel
Jun 5, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Petar MamulaRobert N Baldassano
Feb 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Kelly A BirdwellPeter F Wright
Aug 7, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S CandonL Chatenoud
Dec 29, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J ScharpéW E Peetermans
Jun 16, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·I KaterinisJ Villard
Oct 1, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D KumarUNKNOWN AST Infectious Diseases Community of Practice
Apr 23, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·H J JeonJ Yang
Oct 13, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Peter J MazzoneJanet R Mauer
Apr 25, 2006·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Monika LindemannHans Grosse-Wilde
Sep 12, 2015·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Reza Karbasi-AfsharHossein Khedmat
Jan 1, 1982·Scandinavian Journal of Infectious Diseases·J NikoskelainenA Kasanen
Oct 20, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C BalletJ-P Soulillou
Jun 21, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L C WillcocksK G C Smith
Jan 25, 2012·Nature Reviews. Neurology·Micha LoebermannUwe K Zettl
Aug 10, 2020·Multiple Sclerosis and Related Disorders·John Robert CiottiAnne Haney Cross

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.