Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season

Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Ainara Mira-Iglesias On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease

Abstract

IntroductionInfluenza immunisation is recommended for elderly people each season. The influenza vaccine effectiveness (IVE) varies annually due to influenza viruses evolving and the vaccine composition.AimTo estimate, in inpatients ≥ 60 years old, the 2017/18 trivalent IVE, overall, by vaccine type and by strain. The impact of vaccination in any of the two previous seasons (2016/17 and 2015/16) on current (2017/18) IVE was also explored.MethodsThis was a multicentre prospective observational study within the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI, Spain). The test-negative design was applied taking laboratory-confirmed influenza as outcome and vaccination status as main exposure. Information about potential confounders was obtained from clinical registries and/or by interviewing patients; vaccine information was only ascertained by registries.ResultsOverall, 2017/18 IVE was 9.9% (95% CI: -15.5 to 29.6%), and specifically, 48.3% (95% CI: 13.5% to 69.1%), -29.9% (95% CI: -79.1% to 5.8%) and 25.7% (95% CI: -8.8% to 49.3%) against A(H1N1)pdm09, A(H3N2) and B/Yamagata lineage, respectively. For the adjuvanted and non-adjuvanted vaccines, overall IVE was 10.0% (95% CI...Continue Reading

References

Jul 4, 1998·The Journal of Infectious Diseases·L SimonsenK Fukuda
Feb 16, 2005·Archives of Internal Medicine·Lone SimonsenMark A Miller
Jan 18, 2006·Journal of Epidemiology and Community Health·Bruna GalobardesGeorge Davey Smith
Jul 5, 2008·Journal of Virological Methods·Kamol SuwannakarnYong Poovorawan
Sep 30, 2010·Vaccine·Joan Puig-BarberàUNKNOWN Surveillance and Vaccine Evaluation Group during the autumn 2009 H1N1 pandemic wave in Castellón, Spain
Mar 19, 2013·Vaccine·Michael L Jackson, Jennifer C Nelson
Oct 2, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Huong Q McLeanEdward A Belongia
Oct 29, 2014·Expert Review of Vaccines·Sheena G SullivanBenjamin J Cowling
Mar 6, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·J Puig-BarberaUNKNOWN Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease
Apr 23, 2015·The Journal of General Virology·Carolien E van de SandtMarine L B Hillaire
Feb 21, 2016·Vaccine·Ana Mosterín HöppingDerek J Smith
Mar 23, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allen C ChengUNKNOWN Influenza Complications Alert Network (FluCAN) Investigators
Jun 1, 2017·Expert Review of Vaccines·Edward A BelongiaGaston De Serres
Oct 19, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Marc RondyAlain Moren
Nov 2, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Sheena G SullivanJames E Fielding
Nov 9, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Richard PebodyMaria Zambon
Jan 10, 2018·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Itziar CasadoUNKNOWN Project PI12/02079 Working Group
Jan 13, 2018·The Journal of Infectious Diseases·Karen L LaurieIan G Barr
Feb 8, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Danuta M SkowronskiMel Krajden
Feb 24, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Jesús CastillaUNKNOWN Network For Influenza Surveillance In Hospitals Of Navarre
Mar 1, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Ainara Mira-IglesiasUNKNOWN Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease
Mar 8, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Marc RondyUNKNOWN I-MOVE/I-MOVE+ group
Apr 5, 2018·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Cornelia AdlhochUNKNOWN The European Influenza Surveillance Network

❮ Previous
Next ❯

Citations

Nov 26, 2021·Influenza and Other Respiratory Viruses·Ainara Mira-IglesiasUNKNOWN Valencia Hospital Network for the Study of Influenza and other Respiratory Viruses

❮ Previous
Next ❯

Methods Mentioned

BETA
reverse transcription-PCR
glycosylation

Software Mentioned

VRVIS
BioEdit
Clustal
PhyML
Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Ainara Mira-IglesiasValencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease
Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Marc RondyAlain Moren
Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Jesús CastillaNetwork For Influenza Surveillance In Hospitals Of Navarre
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Fiona P HaversBrendan Flannery
© 2021 Meta ULC. All rights reserved