Influenza vaccine strategies for solid organ transplant recipients

Current Opinion in Infectious Diseases
Cédric Hirzel, D Kumar

Abstract

The aim of this study was to highlight recent evidence on important aspects of influenza vaccination in solid organ transplant recipients. Influenza vaccine is the most evaluated vaccine in transplant recipients. The immunogenicity of the vaccine is suboptimal after transplantation. Newer formulations such as inactivated unadjuvanted high-dose influenza vaccine and the administration of a booster dose within the same season have shown to increase response rates. Intradermal vaccination and adjuvanted vaccines did not show clear benefit over standard influenza vaccines. Recent studies in transplant recipients do not suggest a higher risk for allograft rejection, neither after vaccination with a standard influenza vaccine nor after the administration of nonstandard formulation (high-dose, adjuvanted vaccines), routes (intradermally) or a booster dose. Nevertheless, influenza vaccine coverage in transplant recipients is still unsatisfactory low, potentially due to misinterpretation of risks and benefits. Annual influenza vaccination is well tolerated and is an important part of long-term care of solid organ transplant recipients.

References

Jan 1, 1979·British Medical Bulletin·C W Potter, J S Oxford
Jan 22, 2003·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R A VilchezS Kusne
Jul 6, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Deepali KumarAtul Humar
Feb 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Kelly A BirdwellPeter F Wright
Jul 14, 2010·The Lancet Infectious Diseases·Deepali KumarUNKNOWN American Society of Transplantation H1N1 Collaborative Study Group
Jan 21, 2011·The Pediatric Infectious Disease Journal·Iva HojsakRivka Shapiro
Mar 8, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Oriol ManuelDeepali Kumar
May 27, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Susanne BrakemeierKlemens Budde
Jun 16, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·I KaterinisJ Villard
Sep 13, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S A SchafferH J Ross
Sep 25, 2012·Transplant Infectious Disease : an Official Journal of the Transplantation Society·T FairheadD Kumar
Oct 20, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P Perez-RomeroE Cordero
Feb 15, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A BaluchD Kumar
Mar 8, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L Danziger-IsakovUNKNOWN AST Infectious Diseases Community of Practice
Aug 15, 2014·The New England Journal of Medicine·Carlos A DiazGranadosH Keipp Talbot
Dec 17, 2014·PLoS Pathogens·Adrian EgliDeepali Kumar
Jan 16, 2015·The Journal of Infectious Diseases·Adrian EgliDeepali Kumar
May 7, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·I HelanteräH Isoniemi
Aug 2, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P Pérez-RomeroUNKNOWN Influenza Vaccine in Solid Organ Transplant Recipient Study Group Spanish Network of Research in Infectious Diseases REIPI-G
Dec 27, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Natasha B HalasaMadan Jagasia
Mar 2, 2016·Clinical Transplantation·Ryan M MillerMary S Hayney
Mar 8, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L B VanWagnerD M Lloyd-Jones
Apr 8, 2016·Annals of Transplantation : Quarterly of the Polish Transplantation Society·Birgitta WeltermannKerstin Herzer
Jul 13, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D KumarA Humar
Dec 9, 2016·Human Vaccines & Immunotherapeutics·Vincenzo RestivoFrancesco Vitale
Apr 1, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elisa CorderoUNKNOWN TRANSGRIPE 1–2 Study Group
Aug 12, 2017·Trends in Cardiovascular Medicine·Henri Roukoz, David G Benditt
Aug 26, 2017·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·Lisa A GrohskopfDaniel B Jernigan
Oct 7, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Britta HöckerBurkhard Tönshoff

❮ Previous
Next ❯

Citations

Feb 13, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Cedric HirzelUNKNOWN Influenza in Transplant Study Group
Jan 26, 2021·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Saima AslamLara Danziger-Isakov
Jan 24, 2021·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Cedric HirzelUNKNOWN Influenza in Transplant Study Group
Mar 3, 2021·Current Opinion in Organ Transplantation·Amit I BeryDaniel Kreisel
Feb 11, 2021·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Cedric HirzelDeepali Kumar
Apr 28, 2021·Pediatric Transplantation·Annabelle de St MauriceNatasha Halasa
Jun 12, 2021·Journal of the American Society of Nephrology : JASN·Dominique BertrandSophie Candon
Dec 15, 2021·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Ahmad YanisNatasha B Halasa

❮ Previous
Next ❯

Software Mentioned

TRANSGRIPE

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Pearlie P ChongDavid J Weber
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Oriol ManuelD Kumar
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
D KumarAST Infectious Diseases Community of Practice
Human Vaccines & Immunotherapeutics
Mohammad Bosaeed, D Kumar
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
S B Mossad
© 2022 Meta ULC. All rights reserved