Information processing architecture of functionally defined clusters in the macaque cortex

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Kelly ShenAnthony R McIntosh

Abstract

Computational and empirical neuroimaging studies have suggested that the anatomical connections between brain regions primarily constrain their functional interactions. Given that the large-scale organization of functional networks is determined by the temporal relationships between brain regions, the structural limitations may extend to the global characteristics of functional networks. Here, we explored the extent to which the functional network community structure is determined by the underlying anatomical architecture. We directly compared macaque (Macaca fascicularis) functional connectivity (FC) assessed using spontaneous blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) to directed anatomical connectivity derived from macaque axonal tract tracing studies. Consistent with previous reports, FC increased with increasing strength of anatomical connection, and FC was also present between regions that had no direct anatomical connection. We observed moderate similarity between the FC of each region and its anatomical connectivity. Notably, anatomical connectivity patterns, as described by structural motifs, were different within and across functional modules: partitioning of the functional network ...Continue Reading

Citations

Apr 20, 2013·Brain Connectivity·Emily L Parks, David J Madden
Sep 3, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Corey J KellerAshesh D Mehta
Nov 2, 2013·Science·Hae-Jeong Park, Karl Friston
Jan 7, 2015·Proceedings of the National Academy of Sciences of the United States of America·Pablo BarttfeldStanislas Dehaene
May 6, 2015·Proceedings of the National Academy of Sciences of the United States of America·Kelly ShenMarc G Berman
Nov 25, 2015·Proceedings of the National Academy of Sciences of the United States of America·Maxwell A BertoleroMark D'Esposito
Mar 31, 2016·Trends in Cognitive Sciences·Martijn P van den HeuvelOlaf Sporns
Apr 11, 2014·NeuroImage·Anna E MechlingLaura-Adela Harsan
Oct 23, 2014·Cerebral Cortex·Masanori Shimono, John M Beggs
Sep 17, 2015·Developmental Cognitive Neuroscience·R Matthew Hutchison, J Bruce Morton
Nov 26, 2013·NeuroImage·R Matthew Hutchison, Stefan Everling
Mar 26, 2013·NeuroImage·Klaas Enno Stephan
Apr 23, 2016·Cerebral Cortex·Bratislav MisicOlaf Sporns
Jan 8, 2015·Frontiers in Neuroscience·Lorenzo CaciagliNeda Bernasconi
Apr 16, 2015·PloS One·Zeynep M SayginMargaret Sheridan
Jul 14, 2016·Cerebral Cortex·Maryam GhahremaniStefan Everling
Jul 6, 2016·Journal of Cognitive Neuroscience·Kelly ShenJennifer D Ryan
Aug 31, 2016·Journal of Cognitive Neuroscience·Stefan Fuertinger, Kristina Simonyan
Mar 2, 2017·PLoS Computational Biology·Etay HayAnthony R McIntosh
Mar 4, 2017·Human Brain Mapping·Yongbin WeiMingrui Xia
Oct 31, 2018·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Milou StraathofWillem M Otte
Oct 16, 2015·Nature·Russell A Poldrack, Martha J Farah
Mar 1, 2013·Journal of Neurophysiology·Sahand Babapoor-FarrokhranStefan Everling
Oct 19, 2018·PLoS Computational Biology·Maximilian SchmidtSacha Jennifer van Albada
Jul 15, 2015·Psychosomatic Medicine·John P RyanCaterina Rosano
Jun 26, 2014·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Zhijiang WangYong He
May 1, 2017·Chaos·Federico BattistonVito Latora
Jul 19, 2019·Scientific Data·Kelly ShenAnthony R McIntosh
Dec 26, 2019·Proceedings of the National Academy of Sciences of the United States of America·Graham L BaumTheodore D Satterthwaite
Feb 18, 2021·Scientific Reports·Catherine DuclosStefanie Blain-Moraes
Jan 8, 2021·Network Neuroscience·Zhen-Qi LiuBratislav Misic
Mar 12, 2020·Trends in Cognitive Sciences·Laura E SuárezBratislav Misic
Jul 16, 2014·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Dongmyeong LeeTae-Wook Ko

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.