Informed prognosis [corrected] after abdominal aortic aneurysm repair using predictive modeling techniques [corrected

Journal of Vascular Surgery
V G HadjianastassiouL J Hands

Abstract

To identify the best method for the prediction of postoperative mortality in individual abdominal aortic aneurysm surgery (AAA) patients by comparing statistical modelling with artificial neural networks' (ANN) and clinicians' estimates. An observational multicenter study was conducted of prospectively collected postoperative Acute Physiology and Chronic Health Evaluation II data for a 9-year period from 24 intensive care units (ICU) in the Thames region of the United Kingdom. The study cohort consisted of 1205 elective and 546 emergency AAA patients. Four independent physiologic variables-age, acute physiology score, emergency operation, and chronic health evaluation-were used to develop multiple regression and ANN models to predict in-hospital mortality. The models were developed on 75% of the patient population and their validity tested on the remaining 25%. The results from these two models were compared with the observed outcome and clinicians' estimates by using measures of calibration, discrimination, and subgroup analysis. Observed in-hospital mortality for elective surgery was 9.3% (95% confidence interval [CI], 7.7% to 11.1%) and for emergency surgery, 46.7% (95% CI, 42.5 to 51.0%). The ANN and the statistical models ...Continue Reading

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Citations

Feb 23, 2010·Seminars in Oncology·Robert PatrickMichael W Kattan
Sep 2, 2008·Annals of Vascular Surgery·Marko AleksicJan Brunkwall
Aug 8, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·V G HadjianastassiouL J Hands
Jul 11, 2016·Journal of Biomedical Informatics·Ana Monsalve-TorraMarisol Carreño-Jaimes
Sep 18, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T Y TangJ R Boyle
Apr 4, 2009·Journal of Vascular Surgery·Adam W BeckUNKNOWN Vascular Study Group of Northern New England
Dec 2, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M HenebiensM J W Koelemay
Feb 26, 2020·Journal of Vascular Surgery·Juliette RaffortFabien Lareyre

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European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
T Y TangJ R Boyle
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
V G HadjianastassiouL J Hands
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
V G HadjianastassiouL J Hands
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