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Infrared nanospectroscopic mapping of a single metaphase chromosome

Nucleic Acids Research

Oct 10, 2019

Ewelina LipiecWojciech Maria Kwiatek

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Abstract

The integrity of the chromatin structure is essential to every process occurring within eukaryotic nuclei. However, there are no reliable tools to decipher the molecular composition of metaphase chromosomes. Here, we have applied infrared nanospectroscopy (AFM-IR) to demonstrate molecul...read more

Mentioned in this Paper

Antineoplastic Agents
Malignant Neoplasms
Cell Nucleus
Chromatin
Chromosomes
DNA
Gene Expression
Genome
Heterochromatin
Interphase
2
12
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Infrared nanospectroscopic mapping of a single metaphase chromosome

Nucleic Acids Research

Oct 10, 2019

Ewelina LipiecWojciech Maria Kwiatek

PMID: 31562528

DOI: 10.1093/nar/gkz630

Abstract

The integrity of the chromatin structure is essential to every process occurring within eukaryotic nuclei. However, there are no reliable tools to decipher the molecular composition of metaphase chromosomes. Here, we have applied infrared nanospectroscopy (AFM-IR) to demonstrate molecul...read more

Mentioned in this Paper

Antineoplastic Agents
Malignant Neoplasms
Cell Nucleus
Chromatin
Chromosomes
2
12
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

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