Inguinal metastases from testicular cancer

BJU International
Gedske DaugaardPeter Sommer

Abstract

To evaluate the incidence of inguinal metastases in patients with testicular cancer and relapse after initial stage I disease. Of 695 patients, 14 (2%) with stage I testicular cancer developed inguinal metastases during the follow-up on a surveillance programme. At orchidectomy, one patient had involvement of the tunica albuginea and one a history of cryptorchidism and development of testicular cancer on the contralateral side. The remaining patients had no history of previous surgery in the inguinal region or in the scrotal area, or any other known risk factors for developing inguinal-node metastases. Two patients had a seminoma (0.5%) and 12 (4%) a nonseminoma. The histopathological examination showed that the metastases were in lymph nodes in four patients, the remainder having a more diffuse involvement of the tissue in the inguinal region. At relapse, patients were treated by three or four cycles of bleomycin, etoposide and cisplatin, except those with low-stage seminomas (stage IIa and IIb), who were treated by radiation therapy. All patients had a complete remission after treatment with chemotherapy or radiotherapy. No patients died or developed a recurrence during the median follow-up of 72 months. Metastases to the ing...Continue Reading

References

Jul 1, 1985·The Journal of Urology·M SteinE Robinson
Jan 1, 1986·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G PizzocaroR Musumeci
Mar 1, 1983·Urology·E D CrawfordT A Borden
Jun 1, 1983·The Journal of Urology·J S WheelerR J Krane
Mar 1, 1984·The Journal of Urology·F A KleinH W Herr
May 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M E GelsH Schraffordt Koops
Sep 23, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R FrancisM J Seckl
May 1, 1959·The Journal of Urology·W S WITUSW L VALK
Jan 1, 1963·The Journal of Urology·F M BUSCH, E S SAYEGH

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Citations

Mar 2, 2013·Indian Journal of Surgical Oncology·Shishir Shah, Hemang Bakshi
Feb 13, 2008·Nature Clinical Practice. Urology·Vairavan S SubramanianEric A Klein
Nov 27, 2010·Journal of Medical Case Reports·Mohamed IsmailJunaid Masood
Dec 2, 2015·British Journal of Cancer·Hoi-Hung CheungWai-Yee Chan
Aug 24, 2006·BJU International·Giorgio Bozzini, James G Huang
May 27, 2015·ANZ Journal of Surgery·James Wei Tatt TohScott Mackenzie
Nov 2, 2019·Abdominal Radiology·Aileen O'SheaMukesh G Harisinghani

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