Inhalation of Roman chamomile essential oil attenuates depressive-like behaviors in Wistar Kyoto rats

Science China. Life Sciences
Yingying KongShengtian Li

Abstract

The idea of aromatherapy, using essential oils, has been considered as an alternative antidepressant treatment. In the present study, we investigated the effect of Roman chamomile essential oil inhalation for two weeks on depressive-like behaviors in Wistar-Kyoto (WKY) rats. We found that inhalation of either Roman chamomile or one of its main components α-pinene, attenuated depressive-like behavior in WKY rats in the forced swim test. Using isobaric tags for relative and absolute quantitation analysis (iTRAQ), we found that inhalation of α-pinene increased expression of proteins that are involved in oxidative phosphorylation, such as cytochrome c oxidase subunit 6C-2, cytochrome c oxidase subunit 7A2, ATPase inhibitor in the hippocampus, and cytochrome c oxidase subunit 6C-2, ATP synthase subunit e, Acyl carrier protein, and Cytochrome b-c1 complex subunit 6 in the PFC (prefrontal cortex). In addition, using the quantitative real-time polymerase chain reaction technique, we confirmed an increase of parvalbumin mRNA expression in the hippocampus, which was shown to be upregulated by 2.8-fold in iTRAQ analysis, in α-pinene treated WKY rats. These findings collectively suggest the involvement of mitochondrial functions and parval...Continue Reading

References

Feb 15, 1978·European Journal of Pharmacology·R D PorsoltM Jalfre
Feb 1, 1995·Journal of Neurotrauma·D M BassoJ C Bresnahan
Oct 18, 2000·Complementary Therapies in Nursing & Midwifery·E BurnsL Barnetson
Apr 5, 2002·Journal of Molecular Neuroscience : MN·Andrew HolmesJacqueline N Crawley
Nov 22, 2002·The American Journal of Hospice & Palliative Care·Margaret Louis, Susan D Kowalski
Jun 14, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P H GrahamJ Graham
Feb 5, 2005·Biological Psychiatry·E Fuller TorreyMichael B Knable
Mar 22, 2005·Taehan Kanho Hakhoe chi·Myung-Ja KimSeun-In Paik
May 19, 2005·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M C B NorteC A Lazarini
Apr 22, 2006·Phytotherapy Research : PTR·Diane L McKay, Jeffrey B Blumberg
Oct 26, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Grazyna RajkowskaJose Javier Miguel-Hidalgo
Dec 19, 2006·Trends in Cognitive Sciences·Suzanna Becker, J Martin Wojtowicz
Apr 3, 2008·Current Opinion in Psychiatry·Gerd KempermannKlaus Fabel
Aug 12, 2008·Journal of Affective Disorders·S KoeneE Morava
Nov 4, 2008·Neurochemical Research·Gislaine T RezinEmilio L Streck
May 6, 2010·Journal of Ethnopharmacology·Geun Hee SeolSun Seek Min
Nov 11, 2011·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Ozgür Devrim CanBetül Demirci
Nov 19, 2011·Pharmacognosy Reviews·Ompal SinghManoj Kumar Srivastava
Jan 11, 2012·Methods in Molecular Biology·David H Overstreet
Oct 9, 2012·Science·Ronald S Duman, George K Aghajanian
May 8, 2013·Neuropsychiatric Disease and Treatment·Edward H Tobe
Apr 17, 2015·BMC Complementary and Alternative Medicine·Hyun-Jung ParkChae Ha Yang
Mar 1, 2016·Current Neuropharmacology·Yashika Bansal, Anurag Kuhad
Mar 6, 2016·Journal of Ethnopharmacology·Diandra Araújo LuzEnéas Andrade Fontes-Júnior
Apr 24, 2016·Science China. Life Sciences·Liang YangXingguo Liu
Aug 25, 2016·Behavioural Brain Research·Zsófia VargaBoldizsár Czéh

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Citations

Dec 7, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Jay D AmsterdamJun J Mao
Sep 11, 2020·International Journal of Environmental Research and Public Health·Michele AntonelliFabio Firenzuoli
Aug 31, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Hiroshi UenoTakeshi Ishihara
Dec 15, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Yulu ZhangWei Peng

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