Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma.

The Cochrane Database of Systematic Reviews
J P GuevaraJ Zorc

Abstract

Inhaled corticosteroids (ICS) and sodium cromoglycate (SCG) have become established as effective controller medications for children and adults with asthma, but their relative efficacy is not clear. To compare the relative effectiveness and adverse effects of ICS and SCG among children and adults with chronic asthma. Systematic search of the Cochrane Airways Group's special register of controlled trials (to Feb. 2004), hand searches of the reference lists of included trials and relevant review papers, and written requests for identification of additional trials from pharmaceutical manufacturers. Randomized controlled trials comparing the effect of ICS with SCG in children and adults with chronic asthma. All studies were assessed independently for eligibility by three review authors. Disagreements were settled by consensus. Trial authors were contacted to supply missing data or to verify methods. Eligible studies were abstracted and fixed- and random-effects models were implemented to pool studies. Separate analyses were conducted for paediatric and adult studies. Subgroup analyses and meta-regression models were fit to explore heterogeneity of lung function outcomes by type of RCT, category of ICS or SCG dosage, asthma severity...Continue Reading

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Citations

Feb 2, 2013·American Journal of Respiratory and Critical Care Medicine·Hengameh H RaissyStanley J Szefler
Oct 10, 2008·The Cochrane Database of Systematic Reviews·Johannes C van der WoudenFrancine Ducharme
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May 15, 2018·Frontiers in Immunology·Heather L CaslinJohn J Ryan
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Mar 4, 2008·The Journal of Allergy and Clinical Immunology·Robert S ZeigerMichael Schatz
Jan 13, 2009·Pediatric Clinics of North America·Paul D Robinson, Peter Van Asperen

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