Inherited epigenetic variation--revisiting soft inheritance

Nature Reviews. Genetics
Eric J Richards

Abstract

Phenotypic variation is traditionally parsed into components that are directed by genetic and environmental variation. The line between these two components is blurred by inherited epigenetic variation, which is potentially sensitive to environmental inputs. Chromatin and DNA methylation-based mechanisms mediate a semi-independent epigenetic inheritance system at the interface between genetic control and the environment. Should the existence of inherited epigenetic variation alter our thinking about evolutionary change?

References

Oct 9, 1987·Science·R Holliday
Jul 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·J D Axtell, R A Brink
May 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·R D Ivarie, J A Morris
May 1, 1980·Somatic Cell Genetics·B Kahan, R DeMars
Oct 29, 1996·Proceedings of the National Academy of Sciences of the United States of America·T KakutaniE J Richards
Apr 1, 1997·Current Biology : CB·I RoemerJ Klose
Aug 22, 1997·Science·S E Jacobsen, E M Meyerowitz
Sep 10, 1999·Journal of Theoretical Biology·C Pál, I Miklós
Sep 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·S T SchultzJ H Willis
Nov 5, 1999·Nature Genetics·H D MorganE Whitelaw
Mar 8, 2000·Current Biology : CB·S E JacobsenE M Meyerowitz
Jan 19, 2002·Genes & Development·Trevor L StokesEric J Richards
Jul 19, 2002·The Journal of Biological Chemistry·Nicolas StewardHiroshi Sano
Aug 7, 2002·The Journal of Nutrition·Craig A CooneyGeorge L Wolff
Aug 22, 2002·Proceedings of the National Academy of Sciences of the United States of America·Eric U SelkerHisashi Tamaru
Nov 14, 2002·Annual Review of Genetics·Marcel TijstermanRonald H A Plasterk
Jan 21, 2003·Genesis : the Journal of Genetics and Development·Natasha LaneWolf Reik
Feb 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Vardhman K RakyanEmma Whitelaw
Mar 29, 2003·Genetics·Mark W KankelEric J Richards
Jul 16, 2003·Molecular and Cellular Biology·Robert A Waterland, Randy L Jirtle
Nov 5, 2003·Nature Immunology·Karen W MakarChristopher B Wilson
Apr 6, 2004·Nature Genetics·Catherine M SuterRobyn L Ward
May 22, 2004·Nature Reviews. Genetics·Melissa J Fazzari, John M Greally
Jun 29, 2004·Nature Neuroscience·Ian C G WeaverMichael J Meaney
Jul 23, 2004·Nature·Zachary LippmanRob Martienssen
Oct 19, 2004·Seminars in Cancer Biology·Andrew P Feinberg
Dec 24, 2004·Proceedings of the National Academy of Sciences of the United States of America·Tomoyasu SugiyamaShiv I S Grewal

❮ Previous
Next ❯

Citations

Aug 28, 2010·Cellular and Molecular Life Sciences : CMLS·V A Blomen, J Boonstra
Sep 19, 2009·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Hugh J FrenchRohan B H Williams
Mar 18, 2009·Molecular Genetics and Genomics : MGG·Daniela AhlertRalph Bock
Jul 10, 2012·Molecular Genetics and Genomics : MGG·Sen LiuJiang Feng
Aug 21, 2007·Genetica·Jeanne A Zeh, David W Zeh
Mar 20, 2010·Neurotoxicity Research·Trevor ArcherRichard M Kostrzewa
Mar 24, 2010·Neurotoxicity Research·Eric B Keverne
Jun 19, 2012·Clinical Epigenetics·Tomislav HorvatGordan Lauc
Jan 19, 2013·Sports Medicine·Tobias EhlertDirk A Moser
Jan 19, 2013·Biochimie·Giuseppe Scalabrino, Daniela Veber
Feb 2, 2013·Progress in Biophysics and Molecular Biology·Per Jensen
Oct 8, 2013·Trends in Microbiology·Takao Kasuga, Mark Gijzen
Nov 30, 2011·The Proceedings of the Nutrition Society·Paula Dominguez-SalasSophie E Moore
Jul 23, 2009·Heredity·E Hörandl
May 13, 2010·Heredity·F K Teixeira, V Colot
Jun 11, 2010·Nature·Catherine Dulac
Mar 8, 2013·Nature·Steven Eichten, Justin Borevitz
Jun 22, 2007·Nature Clinical Practice. Endocrinology & Metabolism·Susan E Ozanne, Miguel Constância
May 20, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Jeremy J Day, J David Sweatt
Jan 17, 2008·European Journal of Human Genetics : EJHG·Susanne E BoonenJohanne Md Hahnemann
Apr 11, 2007·Molecular Psychiatry·J Mill, A Petronis
Aug 28, 2012·Proceedings of the National Academy of Sciences of the United States of America·Vicki R NelsonJoseph H Nadeau
Feb 22, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Alex Hankey
Sep 13, 2012·DNA and Cell Biology·Dario Boffelli, David I K Martin
Nov 11, 2010·Briefings in Functional Genomics·Christopher G Bell, Stephan Beck
Nov 3, 2012·Briefings in Functional Genomics·Jadiel A WassonDavid J Katz
Nov 21, 2007·Bioinformatics·Christoph Bock, Thomas Lengauer
Jan 21, 2009·Human Molecular Genetics·James M FlanaganArturas Petronis
Mar 29, 2013·Integrative and Comparative Biology·Andrea L LieblLynn B Martin
Apr 16, 2013·Integrative and Comparative Biology·Aaron W SchreyMarta Robertson
Apr 27, 2013·Integrative and Comparative Biology·Kevin B FloresGro V Amdam
Feb 9, 2008·Molecular Biology and Evolution·Laura Wegener ParfreyLaura A Katz
Jun 17, 2010·Molecular Biology and Evolution·Ovidiu PaunMark W Chase
Aug 16, 2008·Schizophrenia Bulletin·Gabriel Oh, Arturas Petronis
Sep 29, 2009·Schizophrenia Bulletin·Bart P F Rutten, Jonathan Mill
Jul 13, 2007·Current Opinion in Obstetrics & Gynecology·Wen Di, Sun-Wei Guo
Apr 15, 2009·Proceedings. Biological Sciences·Ilaria NegriAlberto Alma
Dec 21, 2012·Proceedings. Biological Sciences·Floriane GuibertCécilia Houdelier
Oct 4, 2013·Proceedings. Biological Sciences·Catherine M SuterDavid I K Martin

❮ Previous
Next ❯

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