PMID: 2503176Jun 24, 1989Paper

Inhibin: a new circulating marker of hydatidiform mole?

BMJ : British Medical Journal
T YohkaichiyaD M de Kretser

Abstract

To define the concentrations of inhibin in serum and tissue of patients with hydatidiform mole and assess their value as a clinical marker of the condition. Prospective study of new patients with hydatidiform mole, comparison of paired observations, and case-control analysis. A university hospital, two large public hospitals, and a private women's clinic in Japan. Seven consecutive referred patients seen over four months with newly diagnosed complete hydatidiform mole, including one in whom the mole was accompanied by viable twin fetuses (case excluded from statistical analysis because of unique clinical features). All patients followed up for six months after evacuation of molar tissue. Correlation of serum inhibin concentrations with trophoblastic disease. Serum concentrations of inhibin, human chorionic gonadotrophin, and follicle stimulating hormone were compared before and seven to 10 days after evacuation of the mole. Before evacuation the serum inhibin concentrations (median 8.3 U/ml; 95% confidence interval 2.4 to 34.5) were significantly greater than in 21 normal women at the same stage of pregnancy (2.8 U/ml; 2.1 to 3.6), and inhibin in molar tissue was also present in high concentrations (578 U/ml cytosol; 158 to 116...Continue Reading

References

Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·K E MayoW Vale
Oct 30, 1986·Biochemical and Biophysical Research Communications·R I McLachlanD M de Kretser
Sep 1, 1988·The Journal of Clinical Endocrinology and Metabolism·D M RobertsonJ K Findlay
Nov 1, 1987·The Journal of Clinical Endocrinology and Metabolism·R I McLachlanD M de Kretser
Jan 16, 1985·Biochemical and Biophysical Research Communications·D M RobertsonD M de Kretser
Apr 1, 1958·The Journal of Obstetrics and Gynaecology of the British Empire·B M HOBSON

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Citations

Mar 5, 1990·Molecular and Cellular Endocrinology·D M de Kretser
Apr 1, 1993·Molecular and Cellular Endocrinology·M ErämaaO Ritvos
Oct 25, 2000·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T HamasakiT Ishimaru
Feb 16, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J Qu, K Thomas
Oct 1, 1996·British Journal of Obstetrics and Gynaecology·E M Wallace, D L Healy
May 20, 1998·Journal of Endocrinological Investigation·P FlorioF Petraglia
Oct 18, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·F KommossH Müntefering
Jun 1, 1994·American Journal of Obstetrics and Gynecology·B CameronH K Tamimi
Mar 1, 1991·American Journal of Obstetrics and Gynecology·T TabeiN Takanashi
Sep 1, 1991·American Journal of Obstetrics and Gynecology·F PetragliaH Meunier
Oct 8, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Katsuyoshi SekiSouei Sekiya
Sep 29, 2004·Molecular and Cellular Endocrinology·P FlorioF Petraglia
Feb 13, 2003·Clinical Endocrinology·Stephen TongHenry G Burger
Dec 1, 1992·Annals of Medicine·H G Burger
Dec 16, 1997·American Journal of Obstetrics and Gynecology·K D WenstromL Boots
May 6, 1998·Histopathology·W G McCluggageJ M Sloan
Aug 1, 1994·Clinical Endocrinology·H G Burger
Feb 24, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·W G McCluggage
Jun 16, 2004·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·H M Hegab, A E Schindler
Jul 2, 2003·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Gale Inoff-GermainJudith L Rapoport
Sep 21, 1989·The New England Journal of Medicine·W J Bremner
Aug 14, 2002·Cancer·Pasquale FlorioFelice Petraglia
Apr 1, 1990·Journal of Endocrinological Investigation·F PetragliaS Angioni
Jul 1, 1990·Journal of Endocrinological Investigation·D M de KretserG P Risbridger

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