Inhibin A-subunit gene expression in the ovaries of immature female rats is stimulated by pregnant mare serum gonadotrophin

Biochemical and Biophysical Research Communications
S R DavisH G Burger

Abstract

We have used a bovine cDNA probe for the A-subunit of inhibin to demonstrate the presence of inhibin in the ovaries of immature female rats: the levels of mRNA were increased following treatment of the rats with pregnant mare serum gonadotrophin (PMSG), suggesting modulation by PMSG of ovarian inhibin synthesis at least at the level of transcription. Furthermore, we report the unexpected finding of significant levels of inhibin mRNA in the corpora lutea of mature female rats. No inhibin mRNA was demonstrable in the uterus or placenta.

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Citations

Oct 1, 1989·Journal of Steroid Biochemistry·S Y Ying
Jan 22, 1990·Molecular and Cellular Endocrinology·A L AlbistonZ S Krozowski
Jun 1, 1990·Baillière's Clinical Endocrinology and Metabolism·D L HealyD De Kretser
Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·H MeunierW Vale
Jul 11, 1991·Clinical Endocrinology·S G HillierA S McNeilly
May 28, 1993·Annals of the New York Academy of Sciences·S G Hillier, F Miró
Jan 1, 1994·In Vitro Cellular & Developmental Biology. Animal·M V AlvaradoI H Russo
Jan 1, 1988·Annals of the New York Academy of Sciences·D T BairdA S McNeilly
May 1, 1988·Australian and New Zealand Journal of Medicine·H G BurgerG T Kovacs
Sep 29, 2004·Molecular and Cellular Endocrinology·J S E Laven, B C J M Fauser
Feb 1, 1987·Baillière's Clinical Endocrinology and Metabolism·R I McLachlanH G Burger
Dec 1, 1988·The Anatomical Record·S V GardeA R Sheth
Dec 1, 1991·Molecular and Cellular Neurosciences·P S Lapolt, A J Hsueh

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