Inhibin B, predictive factor for testicular sperm recovery?

Gynécologie, obstétrique & fertilité
Valérie VernaeveHerman Tournaye

Abstract

Serum inhibin B is a glycoprotein of gonadal origin secreted by the sertoli cells and its secretion is regulated by interaction with the germ cells. Its role as a marker of spermatogenesis is clearly established. Therefore, its role as predictor for finding sperm by surgical testicular sperm retrieval in non-obstructive azoospermia was evaluated as in these patients sperm will only be recovered in half the cases. Our results together with a review of the reports published so far, show that although inhibin B is more accurate in predicting the result of sperm recovery, it cannot predict the outcome of a testicular sperm recovery in patients with non-obstructive azoospermia.

References

Aug 1, 1997·Human Reproduction·P N Schlegel, L M Su
Sep 24, 1998·The Journal of Clinical Endocrinology and Metabolism·F H PierikR F Weber
Aug 6, 2000·Fertility and Sterility·B A KolbR Z Sokol
Feb 6, 2003·Fertility and Sterility·Thilo SchillKlaus Diedrich

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Citations

Jun 18, 2015·Human Reproduction·V VloeberghsH Tournaye
May 9, 2008·Gynécologie, obstétrique & fertilité·N Bourcigaux, S Christin-Maître

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