Inhibins in woman's hypofertility: practical interest

Gynécologie, obstétrique & fertilité
C Coussieu

Abstract

Inhibin B measurement is evolving as a very common prescription in woman's hypofertility diagnosis and follow-up. The aim of this short review of literature is to assess the pertinence of addition of this parameter in the evaluation of the ovarian reserve and in the follow-up of the ovary stimulation treatments. Many studies have been conducted but their results are controversial. According to a majority of authors, inhibin B assay does not systematically bring a discriminant input in borderline clinic cases, already documented by age, plasmatic FSH or even plasmatic estradiol, and echographic evaluation of number of antral follicles on day 3. Most recent publications however grant a growing positive interest in the inhibin B inclusion in the EFORT test as it allows to notably improve the evaluation of the ovarian reserve. Plasma inhibin B assay during the stimulation protocols does not seem to bring significant complementary information and, in any event, cannot be routinely prescribed for a therapeutic follow-up as long as there is no available rapid inhibin assay. Inhibin A evaluation is only performed in research protocols. Research developments regarding the regulation of the post-transfer luteal phase and the implantation...Continue Reading

References

Jan 1, 1997·Fertility and Sterility·D B SeiferC A Berk
Nov 5, 1999·Human Reproduction·S L CorsonM R Soules
Jul 21, 2000·Annals of Clinical Biochemistry·N P Groome, L W Evans
Mar 30, 2001·Reproduction : the Official Journal of the Society for the Study of Fertility·P G Knight, C Glister
Jun 4, 2002·Human Reproduction·M FawzyW R Robertson
Dec 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Corrine K WeltJanet E Hall
Sep 25, 2003·Archives of Gynecology and Obstetrics·Jörg B EngelKlaus Diedrich

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.