Inhibition by serum of autoimmune aspermatogenic orchitis.

The Australian Journal of Experimental Biology and Medical Science
C C BernardG Lamoureux

Abstract

Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea-pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea-pigs' spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea-pigs. In protected animals, cell-mediated immunity and humoral antibodies to antigen P were also significantly suppressed.

Citations

Jul 1, 1982·Journal of Reproductive Immunology·C Y LeeA C Menge

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