PMID: 9184801May 1, 1997Paper

Inhibition of a Porphyromonas gingivalis colonizing factor between Actinomyces viscosus ATCC 19246 by monoclonal antibodies against recombinant 40-kDa outer-membrane protein

General Pharmacology
S SaitoYoshimitsu Abiko

Abstract

1. Porphyromonas gingivalis, an important pathogen in human periodontal disease, aggregates with Actinomyces viscosus ATCC 19246. 2. Monoclonal antibodies (mAbs) against purified recombinant 40-kDa outer-membrane protein (r40-kDa, OMP) of P. gingivalis 381 inhibited its coaggregation with A. viscosus ATCC 19246 in a dose-dependent manner. 3. Five mAb clones against r40-kDa OMP were selected. The isotype of the five was IgG1. 4. Pg-ompA2 inhibited the coaggregation of several strains of P. gingivalis with A. viscosus ATCC 19246 cells.

References

Oct 1, 1979·Journal of Clinical Periodontology·J Slots
Jul 15, 1991·Biochemical and Biophysical Research Communications·M Nishikata, F Yoshimura
Jan 1, 1990·Archives of Oral Biology·Y AbikoH Takiguchi
May 1, 1989·Infection and Immunity·R P Ellen, D A Grove
Mar 1, 1988·Microbiological Reviews·D Mayrand, S C Holt
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Apr 1, 1981·Infection and Immunity·J J ZambonJ Slots
Mar 1, 1984·Journal of Dental Research·I TakazoeK Okuda

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Citations

Feb 24, 2016·Frontiers in Microbiology·Kah Yan HowKok Gan Chan
Dec 19, 2009·Periodontology 2000·Atsuo Amano
Dec 31, 2002·Biochemical and Biophysical Research Communications·Yasuko ShibataYoshimitsu Abiko
May 16, 2009·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Jun SasaharaKenichi Tanaka
May 11, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Y Abiko
Sep 10, 2010·Journal of Periodontal & Implant Science·Jeom-Il Choi, Gregory J Seymour
Aug 3, 2007·Expert Review of Vaccines·Dileep C G SharmaBangalore Varadhan Karthikeyan
Jan 12, 2020·Current Topics in Medicinal Chemistry·Abhishek WadhawanTeodor T Postolache

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