Inhibition of an initiation codon function by hemin deficiency and the hemin-controlled translational repressor in the reticulocyte cell-free system

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Inhibition of an initiation codon function by hemin deficiency and the hemin-controlled translational repressor in the reticulocyte cell-free system

Abstract

References

Isolation of diphtheroid organisms from rheumatoid synovial membrane and fluid

Control of globin synthesis in cell-free preparations of reticulocytes by formation of a translational repressor that is inactivated by hemin

Protein initiation in eukaryotes: formation and function of a ternary complex composed of a partially purified ribosomal factor, methionyl transfer RNA, and guanosine triphosphate

Initiation of eukaryotic protein synthesis: (Met-tRNA f -40S ribosome) initiation complex catalysed by purified initiation factors in the absence of mRNA

Control of protein synthesis in reticulocyte lysates by haemin

Factor-promoted dissociation of free ribosomes in a rabbit reticulocyte lysate system: inhibition and requirement for an energy source

Involvement of hemin, a stimulatory fraction from ribosomes and a protein synthesis inhibitor in the regulation of hemoglobin synthesis

Heterogeneity of the small ribosomal subunit and mechanism of chain initiation in eukaryotes

Control of globin synthesis by hemin: factors influencing formation of an inhibitor of globin chain initiation in reticulocyte lysates

Partial purification of a translational repressor mediating hemin control of globin synthesis and implication of results on the site of inhibition

Protein synthesis in rabbit reticulocytes: control of protein synthesis initiation by a met-tRNA Met f deacylase and peptide chain initiation factors

Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit

Hemin control of globin synthesis: effect of a translational repressor on Met-tRNAf binding to the small ribosomal subunit and its relation to the activity and alailability of an initiation factor

The site of action of inhibitors of initiation of protein synthesis in reticulocytes

Met-tRNA hydrolase from reticulocytes specific for Met-tRNA f Met on 40S ribosomal subunits

A complex between met-tRNA F and native 40S subunits in reticulocyte lysates and its disappearance during incubation with double-stranded RNA

Hemin control of globin synthesis: an assay for the inhibitor formed in the absence of hemin and some characteristics of its formation

Stimulation of globin-chain initiation by hemin in the reticulocyte cell-free system

Inhibition of peptide initiation on reticulocyte ribosomes by edeine

Factors affecting the rate of protein synthesis in lysate systems from reticulocytes

Evidence for an inhibitor in the control of globin synthesis by hemin in a reticulocyte lysate

THE EFFECT OF HEMIN ON THE SYNTHESIS OF GLOBIN

Citations

The control of protein synthesis by hemin in rabbit reticulocytes

The effect of hemin, adenosine 3',5'-monophosphate and phosphorylated sugars on Met-tRNAfMet deacylase activity in rabbit reticulocyte lysates

Met-tRNAfMet binding to 40S ribosomal subunits: a site for the regulation of initiation of protein synthesis by hemin

Partial reaction of peptide initiation inhibited by phosphorylation of either initiation factor eIF-2 or 40S ribosomal proteins

Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection.

Specific hydrolysis of methionyl-tRNA Met f catalyzed by a purified peptide

Benzene inhibition of in vitro rabbit reticulocyte haem synthesis at delta aminolaevulinic acid synthetase: reversal of benzene toxicity by pyridoxine.

Cyclic AMP maintenance of rabbit reticulocyte haem and protein synthesis in the presence of ethanol and benzene

Control of globin synthesis by the haemin-controlled translational repressor in a fractionated cell-free system from rabbit reticulocytes

Translational repression in the control of globin chain initiation by hemin

A rabbit reticulocyte model for the role of hemin-controlled repressor in hypochromic anemias

Partial purification and characterization of a 90,000-dalton peptide involved in activation of the eIF-2 alpha protein kinase of the hemin-controlled translational repressor

Assembly and breakdown of mammalian protein synthesis initiation complexes: regulation by guanine nucleotides and by phosphorylation of initiation factor eIF-2

ATP requirement for binding of 125I-labeled globin mRNA to Artemia salina ribosomes

Reversal of the inhibitory action of the hemin-controlled translational repressor by a post-ribosomal supernatant factor from rabbit reticulocyte lysate

Isolation and characterization of an antibody to a highly purified preparation of the hemin-controlled translational repressor from rabbit reticulocytes

Experimental methyl mercury neurotoxicity: similar in vivo and in vitro perturbation of brain cell-free protein synthesis

Mechanism of inhibition of eukaryotic translational initiation by the trinucleotide ApUpG

Rabbit reticulocyte double-stranded RNA-activated protein kinase and the hemin-controlled translational repressor phosphorylate the same Mr 1500 peptide of eukaryotic initiation factor 2 alpha

The turnover of methionine in the Met-tRNA pool and the control of protein synthesis in reticulocyte lysates: no evidence that haem-deficiency promotes deacylation of Met-tRNAf

Initiation of protein synthesis during lymphocyte stimulation

The molecular mechanism of hemoglobin synthesis and its regulation in the reticulocyte

Inhibition of peptide chain initiation in lysates from ATP-depleted cells. II. Studies on the mechanism of the lesion and its relation to similar alterations caused by oxidized glutathione and hemin deprivation.

Control of protein synthesis by hemin. Isolation and characterization of a supernatant factor from rabbit reticulocyte lysate

Different susceptibility of protein synthesis to inhibitors of elongation in cell-free systems from plasma cell tumours and reticulocytes

Control of globin synthesis by hemin. An intermediate form of the translational repressor in rabbit reticulocyte lysates

Mechanism of inhbition of protein systhesis initiation by diacetoxyscirpenol and fusarenon X in the reticulocyte lysate system

Additional evidence that the hemin-controlled translational repressor from rabbit reticulocytes is a protein kinase.

Inhibition of peptide chain initiation by a nonhemin-regulated translational repressor from Friend leukemia cells.

Benzene and ethanol additive inhibition of rabbit reticulocyte heme and protein synthesis

Isolation of two initiation factors that can partially reverse the inhibition of protein synthesis due to hemin deficiency or the hemin-controlled translational represssor in rabbit reticulocyte lysates.

A functional interaction between methionyl-transfer RNA hydrolase and a transfer RNA binding factor

Translational control of globin synthesis by low molecular weight RNA

Treatment of Chinese hamster ovary cells with the transcriptional inhibitor actinomycin D inhibits binding of messenger RNA to ribosomes

Protein synthesis in rabbit reticulocytes. XII: Requirement of mRNA (AUG codon) for Met-tRNA Met f binding to 40S ribosomes

Partial reaction of peptide initiation inhibited by the reticulocyte hemin-controlled repressor.

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