Inhibition of angiogenesis as a strategy for tumor growth control

Molecular and Chemical Neuropathology
W F Herblin, J F Gross

Abstract

Angiogenesis is a complex sequence of events leading to the formation of new capillaries. Although essential to maturation and wound healing, most angiogenesis in the adult is associated with pathological events, such as the development of solid tumors. One approach to the inhibition of angiogenesis is the antagonism of basic fibroblast growth factor, a major angiogenic protein. Evidence is reviewed to suggest that inhibiting angiogenesis results in the suppression of tumor growth.

References

Jul 1, 1991·Bio/technology·M A Moses, R Langer
Jan 1, 1991·Annals of the New York Academy of Sciences·I VlodavskyZ Fuks
Jan 3, 1990·Journal of the National Cancer Institute·J Folkman
Jul 31, 1990·Biochemical and Biophysical Research Communications·P Bagavandoss, J W Wilks
Mar 1, 1991·The Journal of Surgical Research·E A WolteringJ Fassler
May 15, 1991·Journal of the National Cancer Institute·A WellsteinM E Lippman
Dec 1, 1990·Journal of Neuroscience Research·J L GrossD L Dexter
Dec 20, 1990·The Journal of Steroid Biochemistry and Molecular Biology·R V La RoccaC E Myers
May 1, 1990·Investigational New Drugs·E MissirlisM E Maragoudakis
Jan 23, 1987·Science·J Folkman, M Klagsbrun
Jan 1, 1987·Nouvelle Revue Française D'hématologie·A Camez, G Tobelem
Jun 1, 1989·The Journal of Antibiotics·T YamashitaK Takahashi
Jul 1, 1989·The Journal of Antibiotics·T OikawaT Iwaguchi
Jul 1, 1989·The Journal of Cell Biology·D B Rifkin, D Moscatelli
Nov 18, 1971·The New England Journal of Medicine·J Folkman
Mar 1, 1972·Annals of Surgery·J Folkman
Aug 12, 1971·The New England Journal of Medicine·J Folkman
May 27, 1982·Nature·S Taylor, J Folkman

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