PMID: 43493Oct 1, 1979

Inhibition of aspartate release from the retina of the anaesthetised rabbit by stimulation with light flashes

Neuroscience Letters
M J NealS C Massey


Rabbits were anaesthetised and the cornea, iris, lens and vitreous were removed from eyes to form an eye-cup which was filled with Krebs-bicarbonate Ringer. The medium in the eye-cup was replaced at 10-min intervals and the amino acids in each resulting sample were assayed. Exposure of the dark-adapted retina to flashes of light (3 Hz) did not alter the efflux of glutamate glutamine, alanine, glycine or GABA. The efflux of taurine and ACh was greatly increased by light flashes, but in contrast, the release of aspartate was reduced by more than 50%, a result consistent with the suggestion that aspartate may be a photoreceptor transmitter substance.


Sep 3, 1976·Brain Research·B Ehinger, B Lindberg-Bauer
Dec 1, 1978·Experimental Eye Research·N LakeM J Voaden
Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·S M Wu, J E Dowling
Oct 1, 1976·General Pharmacology·M J Neal
Mar 1, 1976·Journal of Neurochemistry·H T OrrO H Lowry
Oct 12, 1973·Brain Research·B Ehinger


Sep 1, 1981·Neurochemical Research·A M López-Colomé
Apr 23, 1984·Brain Research·A M López-Colomé, F Somohano
Oct 27, 1987·European Journal of Pharmacology·A M López-Colomé, P J Roberts
Jan 1, 1981·Vision Research·B BauerK Tornqvist
Jan 1, 1982·Vision Research·A M López-Colomé, F Somohano
May 1, 1991·Brain Research. Brain Research Reviews·J B Lombardini
Jan 1, 1980·Neurochemistry International·M J Neal, S C Massey
Jan 1, 1987·Progress in Neurobiology·S C Massey, D A Redburn
Feb 6, 1981·Neuroscience Letters·I G Morgan, C A Ingham
Jan 1, 1983·The International Journal of Neuroscience·E Schulze, V Neuhoff
Jun 1, 1984·Experimental Eye Research·C Dawson, M J Neal
Jan 1, 1986·Journal of Neuroscience Research·P SalazarH Pasantes-Morales
Jan 1, 1986·Journal of Neuroscience Research·A M López-Colomé, F Somohano
Jan 10, 2002·Journal of Neuroscience Research·Péter BarabásArne Schousboe

Related Concepts

General Anesthesia
Aspartic Acid, Magnesium-Potassium (2:1:2) Salt
Glycine, Monopotasssium Salt
Synaptic Transmission
Chinchilla Rabbits
Taurine, Monopotassium Salt

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