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Inhibition of gamma-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma

Cancer Chemotherapy and Pharmacology

Jul 1, 2004

P Ruoso, Douglas Hedley

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Abstract

To determine whether gamma-glutamyl transpeptidase (gamma-GT) is involved in the maintenance of elevated cysteine levels in cervical carcinoma. Four cervical carcinoma cell lines were tested in vitro for cysteine accumulation and gamma-GT levels. The highest and lowest gamma-GT-expressi...read more

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  • Inhibition of gamma-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma

    Cancer Chemotherapy and Pharmacology

    Jul 1, 2004

    P Ruoso, Douglas Hedley

    PMID: 15034755

    DOI: 10.1007/s00280-004-0776-3

    Abstract

    To determine whether gamma-glutamyl transpeptidase (gamma-GT) is involved in the maintenance of elevated cysteine levels in cervical carcinoma. Four cervical carcinoma cell lines were tested in vitro for cysteine accumulation and gamma-GT levels. The highest and lowest gamma-GT-expressi...read more

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