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Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits

Parasitology Research

Mar 1, 2008

Rumana Ahmad, Arvind Kumar Srivastava

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Abstract

The rapidly developing resistance to drugs used for prophylaxis and treatment of malaria makes the identification of novel drug targets necessary. Glutathione-S-transferase (GST, E.C. 2.5.1.18), an important enzyme of the glutathione (GSH) cycle, is considered to be an essential detoxif...read more

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  • Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits

    Parasitology Research

    Mar 1, 2008

    Rumana Ahmad, Arvind Kumar Srivastava

    PMID: 18180958

    DOI: 10.1007/s00436-007-0836-9

    Abstract

    The rapidly developing resistance to drugs used for prophylaxis and treatment of malaria makes the identification of novel drug targets necessary. Glutathione-S-transferase (GST, E.C. 2.5.1.18), an important enzyme of the glutathione (GSH) cycle, is considered to be an essential detoxif...read more

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