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Inhibition of human liver beta-galactosidases and beta-glucosidase by n-bromoacetyl-beta-D-galactosylamine

Biochimica Et Biophysica Acta

Dec 18, 1975

Miriam H Meisler

PMID: 1095

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Abstract

N-Bromoacetyl-beta-D-galactosylamine is an irreversible inhibitor of the 'acid' and the 'neutral' beta-galactosidases (beta-D-galactoside galactohydrolase, EC 3.2.1.23) of human liver. The inactivation of acid beta-galactosidase appears to involve a group with a pKa = 4.5. The inhibitio...read more

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Enzymes, antithrombotic
Enzymes, peripheral vasodilators
Inactivation
Glucosidase
Galactosides
Acids
Hydrolase
Galactose Measurement
Dose-Response Relationship, Drug
Enzymes, hematological
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  • Inhibition of human liver beta-galactosidases and beta-glucosidase by n-bromoacetyl-beta-D-galactosylamine

    Biochimica Et Biophysica Acta

    Dec 18, 1975

    Miriam H Meisler

    PMID: 1095

    DOI:

    Abstract

    N-Bromoacetyl-beta-D-galactosylamine is an irreversible inhibitor of the 'acid' and the 'neutral' beta-galactosidases (beta-D-galactoside galactohydrolase, EC 3.2.1.23) of human liver. The inactivation of acid beta-galactosidase appears to involve a group with a pKa = 4.5. The inhibitio...read more

    Mentioned in this Paper

    Enzymes, antithrombotic
    Enzymes, peripheral vasodilators
    Inactivation
    Glucosidase
    Galactosides

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    Paper Details
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